[精子染色体核型分析及减数分裂分离：4种相互易位的研究]
[Spermatozoa karyotyping and meiotic segregation: a study of 4 reciprocal translocations].
作者信息
Pellestor F, Sele B, Jalbert P
机构信息
Laboratoire de Cytogénétique et de Biologie de la Reproduction, Faculté de Médecine de Grenoble, France.
出版信息
J Genet Hum. 1988 Jan;36(1-2):103-6.
Sperm cytogenetics was carried out using technique of in vitro heterospecific human-hamster fertilization. Sperm of 4 men heterozygous from 4 reciprocal translocations (t(4; 17), t(5; 13), t(6; 7) and t(9; 18] was studied. Segregations were various but a majority of unbalanced complements resulting from adjacent 1 segregations was observed. This prevalence was stronger when the pachytene diagram predisposed the translocation to this mode of imbalance at term.
采用体外人-仓鼠异种受精技术进行精子细胞遗传学研究。对4名分别携带4种相互易位（t(4; 17)、t(5; 13)、t(6; 7)和t(9; 18)）的杂合男性的精子进行了研究。分离情况各不相同，但观察到大多数由相邻1型分离产生的不平衡染色体组。当粗线期图显示该易位在足月时倾向于这种不平衡模式时，这种倾向更为明显。
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