Tans J T, Poortvliet D C
Department of Neurology, Westeinde Hospital, The Hague, The Netherlands.
J Neurol Neurosurg Psychiatry. 1988 Apr;51(4):521-5. doi: 10.1136/jnnp.51.4.521.
Reduction of ventricular size was determined by repeated computed tomography in 30 adult patients shunted for normal pressure hydrocephalus (NPH) and related to the pressure-volume index (PVI) and resistance to outflow of cerebrospinal fluid (Rcsf) measured before shunting. Rapid and marked reduction of ventricular size (n = 10) was associated with a significantly lower PVI than slow and moderate to marked (n = 13) or minimal to mild reduction (n = 7). Otherwise no relationship could be found between the reduction of ventricular size and PVI or Rcsf. It is concluded that both rate and magnitude of reduction of ventricular size after shunting for NPH are extremely variable. High brain elasticity seems to be the best predictor of rapid and marked reduction.
通过重复计算机断层扫描确定了30例因正常压力脑积水(NPH)而接受分流术的成年患者的脑室大小缩小情况,并将其与分流术前测量的压力容量指数(PVI)和脑脊液流出阻力(Rcsf)相关联。脑室大小快速且显著缩小(n = 10)与明显低于缓慢且中度至显著缩小(n = 13)或最小至轻度缩小(n = 7)的PVI相关。否则,在脑室大小缩小与PVI或Rcsf之间未发现相关性。得出的结论是,NPH分流术后脑室大小缩小的速度和程度变化极大。高脑弹性似乎是快速且显著缩小的最佳预测指标。