Rutgard J, Frenkel M, Peyman G A, Saks S, Stankevych A
Arch Ophthalmol. 1977 Dec;95(12):2210-3. doi: 10.1001/archopht.1977.04450120116016.
The results of this investigation indicate that 5 X 10(6) and 5 X 10(8) viable bacillus Calmette-Guerin (BCG) organisms (Mycobacterium bovis strain) can be safely administered in the subconjunctival region of the eye of New Zealand albino rabbits without producing toxic effects locally or within the eye. This study provides a format for testing the applicability of BCG immunotherapy for experimental melanomas.
本次调查结果表明,5×10⁶和5×10⁸活卡介苗(BCG)生物体(牛分枝杆菌菌株)可安全地接种于新西兰白化兔眼结膜下区域,不会在局部或眼内产生毒性作用。本研究为测试BCG免疫疗法对实验性黑色素瘤的适用性提供了一种模式。