Wang Huifang, Yu Bo, Zhao Wenjun, Liu Jing
The First Clinical Medical College,Shanxi Medical University,Taiyuan,030001,China.
Department of Thyroid Surgery,the First Hospital of Shanxi Medical University.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Mar;35(3):245-251. doi: 10.13201/j.issn.2096-7993.2021.03.012.
To evaluate the risk factors for metastasis of the lymph nodes posterior to the right recurrent laryngeal nerve in thyroid micropapillary carcinoma(PTMC) by Meta-analysis. We searched domestic and foreign databases for relevant studies published up to June, 2020. Two independent reⅥewers performed literature screening and data extraction according to the inclusion and exclusion criteria. Then, Meta-analysis was performed using Revman 5.3 software. A total of 5 articles were included, with a total of 1884 subjects.The results of the study showed that the rate of lymph node metastasis in PTMC Ⅵb area was 10.8% (203/1884). The risk factors for metastasis included patients' age <45 years old, male, right lobe tumor Diameter ≥0.5 cm, invading the envelope, Ⅵa lymph node metastasis. Ⅵb lymph node dissection is recommended when there exists age<45 years, male sex, right lobe tumor≥0.5 cm, capsular invasion or Ⅵa lymph node metastasis.
通过Meta分析评估甲状腺微小乳头状癌(PTMC)右侧喉返神经后方淋巴结转移的危险因素。我们检索了国内外数据库中截至2020年6月发表的相关研究。两名独立的审阅者根据纳入和排除标准进行文献筛选和数据提取。然后,使用Revman 5.3软件进行Meta分析。共纳入5篇文章,总计1884例受试者。研究结果显示,PTMCⅥb区淋巴结转移率为10.8%(203/1884)。转移的危险因素包括患者年龄<45岁、男性、右叶肿瘤直径≥0.5 cm、侵犯包膜、Ⅵa区淋巴结转移。当存在年龄<45岁、男性、右叶肿瘤≥0.5 cm、包膜侵犯或Ⅵa区淋巴结转移时,建议进行Ⅵb区淋巴结清扫。