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[甲状腺微小乳头状癌Ⅵb区淋巴结转移相关因素分析及术中纳米碳的应用价值]

[Analysis of the factors for the lymph node metastasis in rⅥb region of thyroid micropapillary carcinoma and the application value of intraoperative nano-carbon].

作者信息

Sun Zhenhua, Zhao Zhihong, Jiang Huaping

机构信息

Department of Thyroid and Breast Surgery,Affiliated Hospital of Jiangsu University,Zhenjiang,212000,China.

Department of Otolaryngology Head and Neck Surgery,Affiliated Hospital of Jiangsu University.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Apr;34(4):355-359. doi: 10.13201/j.issn.2096-7993.2020.04.017.

Abstract

To investigate the relationship between lymph node metastasis in rⅥb region and pathological features of papillary thyroid microcarcinoma, and the application value of carbon nanoparticles in the operation for lymph node dissection in rⅥb region. One hundred and seventy-five patients were divided into carbon nanoparticles group and the control group depending on whether carbon nanoparticles were used in the operation. The operation time, the number of central lymph node, the number of rⅥb region lymph node, hypocalcaemia symptom complex and hoarseness after the operaion were compared between the two groups. The lymph node metastasis in the rⅥb region and the pathological features of papillary thyroid microcarcinoma were statistically analyzed. The amount of lymph nodes in Central District and rⅥb region was increased and the probability of parathyroid gland injury was decreased by using nano-carbon. The positive rate of lymph nodes in rⅥb region was not related to age, sex, aspect ratio of nodules and microcalcification, but was related to the tumor size, multifoci and the invasion of the capsule. The evaluation model of lymph node metastasis in rⅥb region was established based on the above three correlative features of color doppler ultrasound. The ROC curve analysis showed that the model had high application value . The tumor size, multiple foci and capsule invasion are risk factors for lymph node metastasis in rⅥb region of thyroid micropapillary carcinoma.

摘要

探讨甲状腺微小乳头状癌Ⅵb区淋巴结转移与病理特征的关系,以及碳纳米颗粒在Ⅵb区淋巴结清扫术中的应用价值。175例患者根据术中是否使用碳纳米颗粒分为碳纳米颗粒组和对照组。比较两组手术时间、中央区淋巴结数量、Ⅵb区淋巴结数量、术后低钙血症综合征及声音嘶哑情况。对Ⅵb区淋巴结转移情况及甲状腺微小乳头状癌病理特征进行统计学分析。使用纳米碳可增加中央区和Ⅵb区淋巴结数量,降低甲状旁腺损伤概率。Ⅵb区淋巴结阳性率与年龄、性别、结节纵横比及微钙化无关,而与肿瘤大小、多灶性及包膜侵犯有关。基于上述彩色多普勒超声的三个相关特征建立了Ⅵb区淋巴结转移评估模型。ROC曲线分析显示该模型具有较高应用价值。肿瘤大小、多灶性及包膜侵犯是甲状腺微小乳头状癌Ⅵb区淋巴结转移的危险因素。

相似文献

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[Clinical application of carbon nanoparticles suspension in operation of papillary thyroid carcinoma].碳纳米颗粒混悬液在甲状腺乳头状癌手术中的临床应用
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Feb;34(2):165-169. doi: 10.13201/j.issn.1001-1781.2020.02.016.
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[Application of carbon nanoparticle in neck Ⅵ lymph node dissection for papillary thyroid carcinoma].[碳纳米颗粒在甲状腺乳头状癌颈部Ⅵ区淋巴结清扫中的应用]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 Jul 20;31(14):1089-1092. doi: 10.13201/j.issn.1001-1781.2017.14.009.

本文引用的文献

4
Multifocality related factors in papillary thyroid carcinoma.甲状腺乳头状癌多灶性相关因素。
Asian J Surg. 2019 Jan;42(1):297-302. doi: 10.1016/j.asjsur.2018.05.004. Epub 2018 Jul 4.
6
Clinical features of poorly differentiated thyroid papillary carcinoma.低分化甲状腺乳头状癌的临床特征
Auris Nasus Larynx. 2019 Jun;46(3):437-442. doi: 10.1016/j.anl.2018.10.001. Epub 2018 Nov 19.

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