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[感觉神经性嗅觉功能障碍的治疗研究进展]

[Research progress in the treatment of sensorineural olfactory dysfunction].

作者信息

Chen Yin, Yu Chenjie, Qian Xiaoyun, Gao Xia

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Apr;35(4):365-370. doi: 10.13201/j.issn.2096-7993.2021.04.019.

Abstract

Sensorineural olfactory dysfunction refers to the reduction or distortion of sensory intensity due to insufficient reception or processing of stimulation by olfactory receptors, olfactory sensory neurons or central nervous system. As olfactory dysfunction can affect patients' physical and mental health and even safety of life and the etiology of sensorineural olfactory dysfunction is complicated, it has great clinical significance for understanding the development of olfactory dysfunction's treatment. This article summarizes the current promising treatment for sensorineural olfactory dysfunction, including drug therapy, cell therapy, gene therapy and olfactory training.

摘要

感音神经性嗅觉功能障碍是指由于嗅觉受体、嗅觉感觉神经元或中枢神经系统对刺激的接收或处理不足而导致感觉强度降低或扭曲。由于嗅觉功能障碍会影响患者的身心健康甚至生命安全,且感音神经性嗅觉功能障碍的病因复杂,了解嗅觉功能障碍治疗的进展具有重要的临床意义。本文综述了目前治疗感音神经性嗅觉功能障碍的有前景的方法,包括药物治疗、细胞治疗、基因治疗和嗅觉训练。

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