• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
[Research progress in the treatment of sensorineural olfactory dysfunction].[感觉神经性嗅觉功能障碍的治疗研究进展]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Apr;35(4):365-370. doi: 10.13201/j.issn.2096-7993.2021.04.019.
2
[The progress of stem cells in the treatment of olfactory dysfunction].[干细胞治疗嗅觉功能障碍的研究进展]
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016 Jul 7;51(7):550-3. doi: 10.3760/cma.j.issn.1673-0860.2016.07.015.
3
[Present status of the treatment for olfactory dysfunction].[嗅觉功能障碍的治疗现状]
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Jul 7;53(7):544-549. doi: 10.3760/cma.j.issn.1673-0860.2018.07.013.
4
Olfaction in dentistry.牙科中的嗅觉。
Oral Dis. 2010 Apr;16(3):221-32. doi: 10.1111/j.1601-0825.2009.01616.x. Epub 2009 Aug 28.
5
Olfaction: anatomy, physiology, and disease.嗅觉:解剖学、生理学与疾病
Clin Anat. 2014 Jan;27(1):54-60. doi: 10.1002/ca.22338. Epub 2013 Nov 22.
6
[Progress in research on olfactory epithelial regeneration].[嗅觉上皮再生的研究进展]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Apr;34(4):381-384. doi: 10.13201/j.issn.2096-7993.2020.04.024.
7
Olfaction.嗅觉。
Proc Am Thorac Soc. 2011 Mar;8(1):46-52. doi: 10.1513/pats.201005-035RN.
8
Peripheral Gene Therapeutic Rescue of an Olfactory Ciliopathy Restores Sensory Input, Axonal Pathfinding, and Odor-Guided Behavior.外周基因治疗挽救嗅觉纤毛病,恢复感觉传入、轴突导向和气味导向行为。
J Neurosci. 2018 Aug 22;38(34):7462-7475. doi: 10.1523/JNEUROSCI.0084-18.2018. Epub 2018 Jul 30.
9
Distortion of olfactory perception: diagnosis and treatment.嗅觉感知障碍:诊断与治疗
Chem Senses. 2002 Sep;27(7):611-5. doi: 10.1093/chemse/27.7.611.
10
Cell-Based Therapy Restores Olfactory Function in an Inducible Model of Hyposmia.基于细胞的疗法可恢复嗅觉减退的诱导模型中的嗅觉功能。
Stem Cell Reports. 2019 Jun 11;12(6):1354-1365. doi: 10.1016/j.stemcr.2019.05.001. Epub 2019 May 30.

引用本文的文献

1
Olfactory dysfunction and the role of stem cells in the regeneration of olfactory neurons.嗅觉功能障碍以及干细胞在嗅觉神经元再生中的作用。
Heliyon. 2024 Apr 18;10(9):e29948. doi: 10.1016/j.heliyon.2024.e29948. eCollection 2024 May 15.

本文引用的文献

1
[Correlation of tissue eosinophil count and modified CT olfactory cleft score and olfactory function in patients with nasal polyps].[鼻息肉患者组织嗜酸性粒细胞计数与改良CT嗅裂评分及嗅觉功能的相关性]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Dec;33(12):1142-1147. doi: 10.13201/j.issn.1001-1781.2019.12.007.
2
Chronic Inflammation Directs an Olfactory Stem Cell Functional Switch from Neuroregeneration to Immune Defense.慢性炎症指导嗅干细胞从神经再生到免疫防御的功能转变。
Cell Stem Cell. 2019 Oct 3;25(4):501-513.e5. doi: 10.1016/j.stem.2019.08.011. Epub 2019 Sep 12.
3
Characterizing functional pathways of the human olfactory system.描述人类嗅觉系统的功能途径。
Elife. 2019 Jul 24;8:e47177. doi: 10.7554/eLife.47177.
4
Olfactory Training Prevents Olfactory Dysfunction Induced by Bulbar Excitotoxic Lesions: Role of Neurogenesis and Dopaminergic Interneurons.嗅觉训练可预防延髓兴奋性损伤引起的嗅觉功能障碍:神经发生和多巴胺能中间神经元的作用。
Mol Neurobiol. 2019 Dec;56(12):8063-8075. doi: 10.1007/s12035-019-1639-6. Epub 2019 Jun 8.
5
[Advances in etiology and pathogenic mechanisms of postviral olfactory dysfunction].[病毒感染后嗅觉功能障碍的病因及发病机制研究进展]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 May;33(5):477-480. doi: 10.13201/j.issn.1001-1781.2019.05.025.
6
Cell-Based Therapy Restores Olfactory Function in an Inducible Model of Hyposmia.基于细胞的疗法可恢复嗅觉减退的诱导模型中的嗅觉功能。
Stem Cell Reports. 2019 Jun 11;12(6):1354-1365. doi: 10.1016/j.stemcr.2019.05.001. Epub 2019 May 30.
7
Clinical practice guidelines for the management of olfactory dysfunction - Secondary publication.嗅觉功能障碍管理临床实践指南——二次发表。
Auris Nasus Larynx. 2019 Oct;46(5):653-662. doi: 10.1016/j.anl.2019.04.002. Epub 2019 May 7.
8
SB203580, a p38MAPK inhibitor, attenuates olfactory dysfunction by inhibiting OSN apoptosis in AR mice (activation and involvement of the p38 mitogen-activated protein kinase in olfactory sensory neuronal apoptosis of OVA-induced allergic rhinitis).SB203580,一种 p38MAPK 抑制剂,通过抑制 AR 小鼠中嗅感觉神经元凋亡来减轻嗅觉功能障碍(p38 丝裂原活化蛋白激酶在卵清蛋白诱导的变应性鼻炎中嗅感觉神经元凋亡中的激活和作用)。
Brain Behav. 2019 Jun;9(6):e01295. doi: 10.1002/brb3.1295. Epub 2019 Apr 30.
9
Effect of intranasal administration of neurotrophic factors on regeneration of chemically degenerated olfactory epithelium in aging mice.经鼻给予神经营养因子对衰老小鼠化学性退变嗅上皮再生的影响
Neuroreport. 2018 Nov 7;29(16):1400-1404. doi: 10.1097/WNR.0000000000001125.
10
Combined VEGF/PDGF improves olfactory regeneration after unilateral bulbectomy in mice.联合使用血管内皮生长因子(VEGF)/血小板衍生生长因子(PDGF)可改善小鼠单侧嗅球切除术后的嗅觉再生。
Neural Regen Res. 2018 Oct;13(10):1820-1826. doi: 10.4103/1673-5374.238713.

[感觉神经性嗅觉功能障碍的治疗研究进展]

[Research progress in the treatment of sensorineural olfactory dysfunction].

作者信息

Chen Yin, Yu Chenjie, Qian Xiaoyun, Gao Xia

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Apr;35(4):365-370. doi: 10.13201/j.issn.2096-7993.2021.04.019.

DOI:10.13201/j.issn.2096-7993.2021.04.019
PMID:33794640
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10128435/
Abstract

Sensorineural olfactory dysfunction refers to the reduction or distortion of sensory intensity due to insufficient reception or processing of stimulation by olfactory receptors, olfactory sensory neurons or central nervous system. As olfactory dysfunction can affect patients' physical and mental health and even safety of life and the etiology of sensorineural olfactory dysfunction is complicated, it has great clinical significance for understanding the development of olfactory dysfunction's treatment. This article summarizes the current promising treatment for sensorineural olfactory dysfunction, including drug therapy, cell therapy, gene therapy and olfactory training.

摘要

感音神经性嗅觉功能障碍是指由于嗅觉受体、嗅觉感觉神经元或中枢神经系统对刺激的接收或处理不足而导致感觉强度降低或扭曲。由于嗅觉功能障碍会影响患者的身心健康甚至生命安全,且感音神经性嗅觉功能障碍的病因复杂,了解嗅觉功能障碍治疗的进展具有重要的临床意义。本文综述了目前治疗感音神经性嗅觉功能障碍的有前景的方法,包括药物治疗、细胞治疗、基因治疗和嗅觉训练。