Tian J, Wei Y X
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 May;33(5):477-480. doi: 10.13201/j.issn.1001-1781.2019.05.025.
Postviral olfactory disorders(PVOD) are one of the most commonly identified causes of olfactory dysfunction. However, its causative agent has yet been identified even though techniques of virus detection have been improved rapidly. It has been reported that some kinds of viruses are able to infect the olfactory neurons directly and result in the infection of central nervous system via olfactory pathway, which suggest the complexity of the pathogenic mechanism of PVOD. In the article, we review the advance in virus identification and pathogenesis of PVOD, which might be helpful to the diagnosis and treatment.
病毒感染后嗅觉障碍(PVOD)是嗅觉功能障碍最常见的病因之一。然而,尽管病毒检测技术迅速发展,其病原体尚未得到确认。据报道,某些病毒能够直接感染嗅觉神经元,并通过嗅觉通路导致中枢神经系统感染,这表明PVOD致病机制的复杂性。在本文中,我们综述了PVOD病毒鉴定和发病机制的研究进展,这可能有助于其诊断和治疗。