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世界上首例磁控生长棒(MCGR)——过去十年的经验教训以及所发现的并发症如何助力该植入物的发展:病例报告

The first magnetically controlled growing rod (MCGR) in the world - lessons learned and how the identified complications helped to develop the implant in the past decade: case report.

作者信息

Cheung Jason Pui Yin, Sze Kam Yim, Cheung Kenneth Man Chee, Zhang Teng

机构信息

Department of Orthopaedics and Traumatology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China.

Department of Mechanical Engineering, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China.

出版信息

BMC Musculoskelet Disord. 2021 Apr 1;22(1):319. doi: 10.1186/s12891-021-04181-0.

Abstract

BACKGROUND

The first magnetically controlled growing rod (MCGR) was implanted in 2009. Since then multiple complications have been identified that have helped drive the development of the MCGR and its surgery. The aim of this report is to illustrate how identified complications in the first MCGR helped with developments in the past decade and to report a unique failure mechanism with stud fracture close to the barrel opening.

CASE PRESENTATION

A 5-year old girl with a scoliosis of 58.5 degrees at T1-9 and 72.8 degrees at T9-L4 had a single MCGR inserted and anchored at T3-4 and L3-4. At postoperative 13 months the MCGR was noted to have lost of distraction between lengthening episodes due to unrestricted turning of the internal magnet. To prevent further loss of distraction, an external magnet was placed outside the skin to prevent the magnet from turning back. The overall balance was suboptimal and after the rod was fully distracted, proximal junctional kyphosis occurred. Subsequently, the MCGR was modified with an internal keeper plate to prevent loss of distraction and a dual set of these rods were implanted when the patient was 9 years old. Extension proximally to C7-T1 was done to manage the proximal junctional kyphosis. Her spinal balance improved and distractions continued. She subsequently developed add-on below and the piston rod was not aligned with the actuator. The lumbar spine was also observed to have autofusion. She subsequently had final fusion surgery performed at the age of 15 from C7-L4 leaving a residual tilt below to avoid fusion to the pelvis. The final extracted rod on the left side indicated the "crooked rod sign" on X-ray and rod dissections revealed a new failure mechanism of stud fracture close to the barrel opening. Body fluids and tissue may infiltrate the rod despite no obvious deformation or fractures resulting in hastened wearing of the threads.

CONCLUSIONS

There are various complications associated with MCGRs that are related to rod design and surgical inexperience. Repeated rod stalling is not recommended with potential stud fracture and "crooked rod sign". Rotor stalling and thread wearing which indicates rod failure still require solutions.

摘要

背景

2009年首次植入磁控生长棒(MCGR)。从那时起,已发现多种并发症,这些并发症推动了MCGR及其手术技术的发展。本报告的目的是说明首例MCGR中发现的并发症如何在过去十年中促进了相关技术的发展,并报告一种靠近套筒开口处螺柱骨折的独特失效机制。

病例介绍

一名5岁女孩,T1 - 9节段脊柱侧弯58.5度,T9 - L4节段脊柱侧弯72.8度,在T3 - 4和L3 - 4处植入并固定了一根MCGR。术后13个月,由于内部磁体不受限制地转动,发现MCGR在延长周期之间失去了撑开力。为防止撑开力进一步丧失,在皮肤外放置了一个外部磁体以防止磁体反转。整体平衡不理想,在棒完全撑开后,出现了近端交界性后凸。随后,对MCGR进行了改进,增加了一个内部固定板以防止撑开力丧失,并在患者9岁时植入了两组这样的棒。向近端延伸至C7 - T1以处理近端交界性后凸。她的脊柱平衡得到改善,撑开操作继续进行。随后她出现了下方附加问题,活塞杆与驱动器未对齐。还观察到腰椎出现了自发融合。她随后在15岁时接受了从C7 - L4的最终融合手术,在下方留下了残余倾斜以避免融合到骨盆。左侧最终取出的棒在X射线上显示出“弯曲棒征”,棒的解剖显示出一种靠近套筒开口处螺柱骨折的新失效机制。尽管没有明显的变形或骨折,但体液和组织可能会渗入棒中,导致螺纹加速磨损。

结论

MCGR存在各种与棒设计和手术经验不足相关的并发症。不建议反复进行棒的撑开操作,因为可能会出现螺柱骨折和“弯曲棒征”。转子停滞和螺纹磨损表明棒失效,这仍然需要解决办法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf4d/8015050/e78468afb0fa/12891_2021_4181_Fig1_HTML.jpg

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