Dinman B D
Department of Industrial Environmental Health Sciences, Graduate School of Public Health, University of Pittsburgh, PA 15261.
J Occup Med. 1988 Apr;30(4):328-35.
A review of experimental studies suggests that the catalytically active low temperature transitional forms of alumina produces irreversible fibronodular change only when administered by intratracheal insufflation. Other aluminas not catalytically active but also broadly identified as "gamma" for different reasons also appear capable of inducing pulmonary fibrosis in the same model. Under conditions of human exposure, occupational exposure to a broad range of aluminas indicates--at most--minimal pulmonary nodular response.
一项对实验研究的综述表明，具有催化活性的低温过渡形式氧化铝仅在经气管内注入时才会产生不可逆的纤维结节性改变。其他不具有催化活性但因不同原因也被广泛认定为“γ”的氧化铝，在同一模型中似乎也能够诱发肺纤维化。在人类接触的条件下，职业性接触多种氧化铝至多显示出轻微的肺结节反应。
