Bean D J, Hollis J M, Woo S L, Convery F R
Division of Orthopaedics and Rehabilitation, University of California, San Diego.
J Orthop Res. 1988;6(4):580-4. doi: 10.1002/jor.1100060416.
There is at present great uncertainty relating to the fixation of joint implants. The deficiencies of acrylic bone cement are well documented, but the limitations of cementless fixation are as yet imcompletely identified. The purpose of this study was to investigate the potential of sustained external pressurization to improve the mechanical characteristics of conventional acrylic bone cement. The effect of serially increasing sustained pressurization of two commerically available acrylic bone cements (Simplex-P and LVC) was evaluated in human cadaver femora. A new method for determination of the shear strength of the bone-cement interface in place of the traditional pushout tests was used. In this model, there was a significant increase in the bone-cement interfacial shear strength with increasing pressure, but no difference in the shear strength was found between the two cements. At all pressure levels, the shear strength of the cement was greater than that previously reported. Increased cement penetration into the cortical bone was demonstrated with increasing pressure and low-viscosity cement, but the extent of cement penetration did not correlate with the shear strength of the bone-cement interface.
目前，关节植入物的固定存在很大的不确定性。丙烯酸骨水泥的缺点已有充分记录，但非骨水泥固定的局限性尚未完全明确。本研究的目的是探讨持续外部加压改善传统丙烯酸骨水泥力学性能的潜力。在人类尸体股骨中评估了两种市售丙烯酸骨水泥（Simplex-P和LVC）持续加压递增的效果。采用了一种新方法来测定骨水泥界面的剪切强度，以取代传统的推出试验。在该模型中，随着压力增加，骨水泥界面剪切强度显著增加，但两种骨水泥之间的剪切强度没有差异。在所有压力水平下，骨水泥的剪切强度均高于先前报道的强度。随着压力增加和使用低粘度骨水泥，骨水泥向皮质骨的渗透增加，但骨水泥的渗透程度与骨水泥界面的剪切强度无关。
