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表现为复发性眶周蜂窝织炎的鼻型结外NK/T细胞淋巴瘤

Nasal-type extranodal NK/T-cell lymphoma presenting as recurrent periorbital cellulitis.

作者信息

Hussein Mansoor Ali, Boyle Seamus, Abdulrahman Shawkat, Fennessy Brendan

机构信息

otolaryngology, Tallaght Hospital, Dublin, Ireland

Otolaryngology, Tallaght University Hospital, Dublin, Dublin, Ireland.

出版信息

BMJ Case Rep. 2021 Apr 1;14(4):e238113. doi: 10.1136/bcr-2020-238113.

Abstract

Nasal-type extranodal natural killer/T-cell lymphoma (ENKTCL) is a rare disease with a poor prognosis. It has features similar to other granulomatous and infectious diseases of the nose and paranasal sinuses, which can make diagnosis challenging and delayed. We present a case of 38-year-old man who was admitted to the hospital on three occasions over a 3-month period for right periorbital erythema, nasal congestion and discharge. Following two separate surgical debridement and biopsies, ENKTCL was diagnosed and the patient was commenced on chemoradiotherapy. The case highlights the atypical nature of his presentation and the high degree of suspicion for a pathological process that must be maintained to formulate the diagnosis.

摘要

鼻型结外自然杀伤细胞/ T细胞淋巴瘤(ENKTCL)是一种预后较差的罕见疾病。它具有与其他鼻部和鼻窦肉芽肿性及感染性疾病相似的特征,这可能导致诊断具有挑战性且出现延迟。我们报告一例38岁男性患者,在3个月内3次入院,表现为右侧眶周红斑、鼻塞和流涕。经过两次单独的手术清创和活检后,确诊为ENKTCL,患者开始接受放化疗。该病例突出了其临床表现的非典型性以及在诊断过程中必须对病理过程保持高度怀疑。

相似文献

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Extranodal NK/T-cell lymphoma, nasal type: report of 15 cases.结外 NK/T 细胞淋巴瘤,鼻型:15 例报告。
Eur Ann Otorhinolaryngol Head Neck Dis. 2012 Jun;129(3):141-7. doi: 10.1016/j.anorl.2011.08.004. Epub 2012 Feb 7.

本文引用的文献

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The diagnosis and management of NK/T-cell lymphomas.NK/T细胞淋巴瘤的诊断与管理
J Hematol Oncol. 2017 Apr 14;10(1):85. doi: 10.1186/s13045-017-0452-9.
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NHL - Extranodal T-cell lymphoma.非霍奇金淋巴瘤 - 结外T细胞淋巴瘤
Natl J Maxillofac Surg. 2015 Jan-Jun;6(1):99-102. doi: 10.4103/0975-5950.168217.

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