Devi Seema, Sinha Richi, Singh Rakesh Kumar, Mehta Gagan
Department of Radiation Oncology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India.
Department of Otolaryngology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India.
Natl J Maxillofac Surg. 2015 Jan-Jun;6(1):99-102. doi: 10.4103/0975-5950.168217.
Extranodal NK/T-cell lymphoma, nasal type (ENKL) is a rare lymphoid neoplasm that in the past has been grouped with a variety of granulomatous diseases. ENKL occurs in all age groups. However, it seems to occur more often in people in their 50s and affects more men than women. It is strongly linked to the Epstein-Barr virus (EBV), especially in people of Asian countries. Because this type of lymphoma occurs in organs or tissues other than lymph nodes, it is called ENKL. This is a case report of a 25-year-old female patient who presented with a nonhealing ulcer at the right nasal ala involving the upper lip and cheek for the last 2 months, which had been treated with antitubercular treatment without success. After biopsy and immunohistochemical (IHC) analysis, the patient had been diagnosed a case of extranodal T-cell lymphoma.
结外NK/T细胞淋巴瘤,鼻型(ENKL)是一种罕见的淋巴样肿瘤,过去曾被归类于多种肉芽肿性疾病。ENKL可发生于所有年龄组。然而,它似乎更常发生于50多岁的人群,且男性受累多于女性。它与爱泼斯坦-巴尔病毒(EBV)密切相关,尤其是在亚洲国家的人群中。由于这种类型的淋巴瘤发生于淋巴结以外的器官或组织,因此称为ENKL。这是一例25岁女性患者的病例报告,该患者右鼻翼出现不愈合溃疡,累及上唇和面颊,持续2个月,接受抗结核治疗无效。经活检和免疫组织化学(IHC)分析,该患者被诊断为结外T细胞淋巴瘤。