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胃黏膜相关淋巴组织(MALT)淋巴瘤:50 例患者的临床病理研究和治疗结果。

Gastric mucosa-associated lymphoid tissue (MALT) lymphoma: clinicopathological study and treatment outcome in 50 patients.

机构信息

Pathology Department, Salah Azaiez Institute, Tunis, Tunisia.

Medical Oncology Department, Salah Azaiez Institute, Tunis, Tunisia.

出版信息

Pan Afr Med J. 2020 Dec 23;37:372. doi: 10.11604/pamj.2020.37.372.27094. eCollection 2020.

Abstract

The stomach is the most frequent site of extranodal lymphoma. Mucosa-associated lymphoid tissue (MALT) lymphoma is a low-grade, B-cell neoplasm strongly associated with Helicobacter pylori (HP) infection. The presenting complaints of gastric MALT lymphoma are usually nonspecific. HP eradication is regarded as the first-line therapy in early stage disease. Management of patients who failed to achieve remission following HP eradication include chemotherapy, radiotherapy and in selected cases, surgery. The aim of the present study was to examine the clinical characteristics and treatment outcome of patients with gastric MALT lymphoma.

摘要

胃是结外淋巴瘤最常见的部位。黏膜相关淋巴组织(MALT)淋巴瘤是一种低度恶性、B 细胞肿瘤,与幽门螺杆菌(HP)感染密切相关。胃 MALT 淋巴瘤的首发症状通常无特异性。HP 根除被认为是早期疾病的一线治疗方法。HP 根除治疗失败患者的管理包括化疗、放疗以及在某些情况下手术。本研究旨在探讨胃 MALT 淋巴瘤患者的临床特征和治疗结果。

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本文引用的文献

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Clinical aspects and therapy of gastrointestinal MALT lymphoma.胃肠道黏膜相关淋巴组织淋巴瘤的临床特征与治疗
Best Pract Res Clin Haematol. 2017 Mar-Jun;30(1-2):109-117. doi: 10.1016/j.beha.2017.01.002. Epub 2017 Jan 30.
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