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全眼前节和视网膜扫频源光学相干断层扫描用于全面眼部筛查。

Whole anterior segment and retinal swept source OCT for comprehensive ocular screening.

作者信息

Rodríguez-Aramendía Ana, Díaz-Doutón Fernando, Fernández-Trullàs José, Falgueras Pol, González Laura, Pujol Jaume, Grulkowski Ireneusz, Güell José Luis

机构信息

Instituto de Microcirugía Ocular (IMO), Josep María Lladó 3, Barcelona 08035, Spain.

Center for Sensors, Instruments and Systems Development (CD6), Universitat Politècnica de Catalunya (UPC), Rambla Sant Nebridi 10, Terrassa 08222, Barcelona, Spain.

出版信息

Biomed Opt Express. 2021 Feb 5;12(3):1263-1278. doi: 10.1364/BOE.414592. eCollection 2021 Mar 1.

DOI:10.1364/BOE.414592
PMID:33796352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7984787/
Abstract

Whole eye visualization and morphometry are of high relevance in clinical practice. However, most standard ophthalmic OCT instruments are dedicated either to retinal or to anterior segment imaging. We demonstrate a swept source optical coherence tomography system (SS-OCT) that images both the whole anterior segment and the retina alternately using a single source and detector. A pilot population was imaged with the proof of concept prototype. We demonstrate the clinical potential of whole eye OCT screening for the description and early detection of relevant clinical features in the anterior segment and retina of several patients.

摘要

全眼可视化和形态测量在临床实践中具有高度相关性。然而,大多数标准眼科光学相干断层扫描(OCT)仪器要么专门用于视网膜成像,要么专门用于眼前节成像。我们展示了一种扫频光学相干断层扫描系统(SS-OCT),该系统使用单个光源和探测器交替对整个眼前节和视网膜进行成像。使用概念验证原型对一组试点人群进行了成像。我们展示了全眼OCT筛查在描述和早期检测多名患者眼前节和视网膜相关临床特征方面的临床潜力。

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本文引用的文献

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In vivo SS-OCT imaging of crystalline lens sutures.晶状体缝线的体内扫频光学相干断层扫描成像
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Biomed Opt Express. 2020 May 19;11(6):3164-3180. doi: 10.1364/BOE.392849. eCollection 2020 Jun 1.
3
Study 1: Evaluation of the signs of deficient posterior capsule in posterior polar cataracts using anterior segment optical coherence tomography.研究 1:应用眼前节光学相干断层扫描评估后极性白内障后囊膜缺损的征象。
J Cataract Refract Surg. 2020 Sep;46(9):1260-1265. doi: 10.1097/j.jcrs.0000000000000246.
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Three-dimensional visualization of opacifications in the murine crystalline lens by in vivo optical coherence tomography.通过活体光学相干断层扫描对小鼠晶状体混浊进行三维可视化。
Biomed Opt Express. 2020 Mar 19;11(4):2085-2097. doi: 10.1364/BOE.387335. eCollection 2020 Apr 1.
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Clinical observation of a novel technique: transscleral suture fixation of a foldable 3-looped haptics one-piece posterior chamber intraocular lens implantation through scleral pockets with intact conjunctiva.一种新技术的临床观察:经巩膜袋在结膜完整的情况下通过巩膜袋对可折叠三袢式襻一体式后房型人工晶状体植入进行经巩膜缝线固定术。
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PLoS One. 2018 Oct 2;13(10):e0204501. doi: 10.1371/journal.pone.0204501. eCollection 2018.