Lu Chen D, Waheed Nadia K, Witkin Andre, Baumal Caroline R, Liu Jonathan J, Potsaid Benjamin, Joseph Anthony, Jayaraman Vijaysekhar, Cable Alex, Chan Kinpui, Duker Jay S, Fujimoto James G
Ophthalmic Surg Lasers Imaging Retina. 2018 Feb 1;49(2):94-102. doi: 10.3928/23258160-20180129-03.
To demonstrate the feasibility of retinal and anterior segment intraoperative widefield imaging using an ultrahigh-speed, swept-source optical coherence tomography (SS-OCT) surgical microscope attachment.
A prototype post-objective SS-OCT using a 1,050-nm wavelength, 400 kHz A-scan rate, vertical cavity surface-emitting laser (VCSEL) light source was integrated to a commercial ophthalmic surgical microscope after the objective. Each widefield OCT data set was acquired in 3 seconds (1,000 × 1,000 A-scans, 12 × 12 mm for retina and 10 × 10 mm for anterior segment).
Intraoperative SS-OCT was performed in 20 eyes of 20 patients. In six of seven membrane peels and five of seven rhegmatogenous retinal detachment repair surgeries, widefield retinal imaging enabled evaluation pre- and postoperatively. In all seven cataract cases, anterior imaging evaluated the integrity of the posterior lens capsule.
Ultrahigh-speed SS-OCT enables widefield intraoperative viewing in the posterior and anterior eye. Widefield imaging visualizes ocular structures and pathology without requiring OCT realignment. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:94-102.].
证明使用超高速扫频源光学相干断层扫描（SS-OCT）手术显微镜附件进行视网膜和眼前节术中广角成像的可行性。
一个使用1050纳米波长、400千赫兹A扫描速率、垂直腔面发射激光器（VCSEL）光源的物镜后置式SS-OCT原型被集成到一台商用眼科手术显微镜的物镜之后。每个广角OCT数据集在3秒内采集完成（1000×1000次A扫描，视网膜为12×12毫米，眼前节为10×10毫米）。
对20例患者的20只眼进行了术中SS-OCT检查。在7例膜剥离手术中的6例以及7例孔源性视网膜脱离修复手术中的5例，广角视网膜成像能够进行术前和术后评估。在所有7例白内障病例中，眼前节成像评估了晶状体后囊的完整性。
超高速SS-OCT能够实现眼后段和眼前段的术中广角观察。广角成像无需重新调整OCT即可显示眼部结构和病变。[《眼科手术、激光与影像学杂志》。2018年；49：94 - 102。]
