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手术解除良性前列腺梗阻后保留顺行性射精是一个有效的终点。

Preservation of antegrade ejaculation after surgical relief of benign prostatic obstruction is a valid endpoint.

机构信息

Department of Urology, Faculty of Medicine, Medipol Mega University Hospital, Istanbul Medipol University, Istanbul, Turkey.

Department of Urology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.

出版信息

World J Urol. 2021 Jul;39(7):2277-2289. doi: 10.1007/s00345-021-03682-w. Epub 2021 Apr 1.

Abstract

PURPOSE

To review the current data on retrograde ejaculation (RE) and ejaculatory dysfunction (EjD) after endoscopic and minimally invasive surgical treatment of benign prostatic obstruction (BPO) and, their perceived impact in the quality of life (QoL) and sexual life of patients and their partners.

METHODS

Narrative review of systematic reviews (SR) assessing comparative rates of RE, EjD or erectile dysfunction (EF) was carried out. Relevant articles on the prevalence of RE, EjD or EF and on their impact in the QoL or sexual life of patients and partners were manually selected based on relevance.

RESULTS

Twelve SRs reporting on comparisons of different endoscopic/minimally invasive treatments of BPO were found. Data on outcomes varied widely. Overall, after conventional TURP or laser techniques 42-75% of patients present RE. Prostatic incision and ablative procedures present lowest rates of de novo RE or EjD whereas laser adenomectomy and ejaculation preservation procedures preserve antegrade ejaculation in 46-68% of patients. EjDs is associated to LUTS and present in 10% of sexualy active men before intervention. It modulates the QoL and sexual life of the couple. In spite of the scarce literature assessing patient's and partner's perception of postoperative EjD, it strongly suggests that both parties value the maintenance of the ejaculatory function.

CONCLUSION

Ejaculation-preserving techniques and minimally invasive techniques successfully prevent BPO treatment-induced RE or EjD in 70-100% of the cases. While this is appealing to patients and spouses, technique selection and treatment durability are issues to be discussed with the couple.

摘要

目的

回顾经内镜和微创外科治疗良性前列腺梗阻(BPO)后逆行射精(RE)和射精功能障碍(EjD)的现有数据,以及它们对患者及其伴侣生活质量(QoL)和性生活的影响。

方法

对评估 RE、EjD 或勃起功能障碍(EF)的比较发生率的系统评价(SR)进行叙述性回顾。根据相关性,手动选择有关 RE、EjD 或 EF 的流行率以及对患者及其伴侣的 QoL 或性生活的影响的相关文章。

结果

发现 12 篇报道不同内镜/微创治疗 BPO 的比较的 SR。关于结局的数据差异很大。总体而言,经传统 TURP 或激光技术治疗后,42-75%的患者出现 RE。前列腺切开和消融术新发 RE 或 EjD 发生率最低,而激光前列腺切除术和射精保留术可使 46-68%的患者保持顺行射精。 EjD 与 LUTS 相关,在干预前 10%的活跃男性中存在 EjD。它会影响患者及其伴侣的生活质量和性生活。尽管很少有文献评估患者和伴侣对术后 EjD 的看法,但强烈表明双方都重视保持射精功能。

结论

射精功能保留技术和微创技术可成功预防 70-100%的 BPO 治疗引起的 RE 或 EjD。虽然这对患者和配偶有吸引力,但技术选择和治疗持久性是需要与夫妇讨论的问题。

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