Urology Department, University Hospital of Angers, CHU Angers, 4 rue Larrey, 49933, Angers Cedex 9, France.
Urology Department, University Hospital of Nimes, 30900, Nîmes, France.
World J Urol. 2019 Feb;37(2):299-308. doi: 10.1007/s00345-018-2368-6. Epub 2018 Jul 2.
Ejaculatory dysfunction is the most common side effect related to surgical treatment of benign prostatic obstruction (BPO). Nowadays, modified surgical techniques and non-ablative techniques have emerged with the aim of preserving antegrade ejaculation. Our objective was to conduce a systematic review of the literature regarding efficacy on ejaculatory preservation of modified endoscopic surgical techniques, and mini-invasive non-ablatives techniques for BPO management.
A systematic review of the literature was carried out on the PubMed database using the following MESH terms: "Prostatic Hyperplasia/surgery" and "Ejaculation", in combination with the following keywords: "ejaculation preservation", "photoselective vaporization of the prostate", "photoselective vapo-enucleation of the prostate", "holmium laser enucleation of the prostate", "thulium laser", "prostatic artery embolization", "urolift", "rezum", and "aquablation".
The ejaculation preservation rate of modified-TURP ranged from 66 to 91%. The ejaculation preservation rate of modified-prostate photo-vaporization ranged from 87 to 96%. The only high level of evidence studies available compared prostatic urethral lift (PUL) and aquablation versus regular TURP in prospective randomized-controlled trials. The ejaculation preservation rate of either PUL or aquablation compared to regular TURP was 100 and 90 versus 34%, respectively.
Non-ablative therapies and modified endoscopic surgical techniques seemed to be reasonable options for patients eager to preserve their ejaculatory functions.
射精功能障碍是与良性前列腺梗阻 (BPO) 手术治疗相关的最常见副作用。如今,出现了改良的手术技术和非消融技术,旨在保留顺行射精。我们的目的是对改良内镜手术技术和微创非消融技术在 BPO 管理中对射精功能保留的疗效进行系统评价。
在 PubMed 数据库中使用以下 MESH 术语进行系统的文献回顾:“前列腺增生/手术”和“射精”,并结合以下关键词:“射精功能保留”、“前列腺选择性光汽化术”、“前列腺选择性光汽化切除术”、“钬激光前列腺剜除术”、“铥激光”、“前列腺动脉栓塞术”、“UroLift”、“Rezum”和“Aquablation”。
改良 TURP 的射精保留率为 66%至 91%。改良前列腺光汽化术的射精保留率为 87%至 96%。唯一的高级别证据研究比较了前瞻性随机对照试验中前列腺尿道悬吊术 (PUL) 和 Aquablation 与常规 TURP 的疗效。与常规 TURP 相比,PUL 或 Aquablation 的射精保留率分别为 100%和 90%对 34%。
非消融治疗和改良内镜手术技术似乎是渴望保留射精功能的患者的合理选择。