Chen Hongyan, Wei Shiqi, Wang Ruili, Zhu Meifang
State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, International Joint Laboratory for Advanced Fiber and Low-Dimension Materials, College of Material Science and Engineering, Donghua University, Shanghai 201620, P.R. China.
ACS Biomater Sci Eng. 2021 Apr 12;7(4):1428-1437. doi: 10.1021/acsbiomaterials.1c00152. Epub 2021 Apr 2.
Endowing dental composites with excellent interfacial bonding through filler surface modification is pivotal to improve the physical-mechanical property and prolong the life of composite fillings. In this study, methacrylate-polyhedral oligomeric silsesquioxane (MA-POSS) acts as a "molecular bridge" between the commonly used SiO particles and the methacrylate-based resin matrix via a thiol-ene click reaction to construct MA-POSS/SiO (p-SiO) hybrid particles. Synthesized p-SiO exhibited the roughest surface morphology and had more polymerizable groups, in comparison with SiO and silanized SiO. Furthermore, the p-SiO particles were used as a reinforcement to fabricate bisphenol A glycerolate dimethacrylate/tri(ethyleneglycol) dimethacrylate-based dental composites, where the SiO- and silanized SiO-filled composites served as the control groups, and the filler loading was fixed at 65 wt %. Results of the mechanical properties indicated that the hybrid p-SiO particles significantly improved the flexural strength, flexural modulus, compressive strength, and work of fracture of dental composites, giving improvements of 251.2, 17.89, 122.3, and 1094%, respectively, over the SiO-filled composites due to the strong interfacial interaction between the resin matrix and p-SiO. Additionally, this optimal p-SiO-loaded composite also presented better polymerization shrinkage, acceptable degree of conversion, curing depth, and cell viability. Grafting of MA-POSS onto a filler surface is a promising filler surface modification to improve the resin matrix/filler interfacial interaction, leading to the enhanced overall performance of composites.
通过填料表面改性赋予牙科复合材料优异的界面粘结性能，对于改善其物理机械性能和延长复合填充物的使用寿命至关重要。在本研究中，甲基丙烯酸酯基多面体低聚倍半硅氧烷（MA-POSS）通过硫醇-烯点击反应，在常用的SiO颗粒与甲基丙烯酸酯基树脂基体之间充当“分子桥”，以构建MA-POSS/SiO（p-SiO）杂化颗粒。与SiO和硅烷化SiO相比，合成的p-SiO呈现出最粗糙的表面形态且具有更多可聚合基团。此外，将p-SiO颗粒用作增强剂来制备双酚A甘油酸酯二甲基丙烯酸酯/三（乙二醇）二甲基丙烯酸酯基牙科复合材料，其中SiO填充和硅烷化SiO填充的复合材料作为对照组，填料含量固定为65 wt%。力学性能结果表明，由于树脂基体与p-SiO之间的强界面相互作用，杂化p-SiO颗粒显著提高了牙科复合材料的弯曲强度、弯曲模量、压缩强度和断裂功，与SiO填充的复合材料相比，分别提高了251.2%、17.89%、122.3%和1094%。此外，这种最佳p-SiO负载的复合材料还表现出更好的聚合收缩率、可接受的转化率、固化深度和细胞活力。将MA-POSS接枝到填料表面是一种很有前景的填料表面改性方法，可改善树脂基体/填料界面相互作用，从而提高复合材料的整体性能。
