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一种罕见且不寻常的霍乱弧菌非 O1、非 O139 引起肝硬化患者自发性腹膜炎的病因。

A rare and unusual cause of Vibrio cholerae non-O1, non-O139 causing spontaneous peritonitis in a patient with cirrhosis.

机构信息

Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.

Hospital Universiti Sains Malaysia, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.

出版信息

Trop Biomed. 2021 Mar 1;38(1):183-186. doi: 10.47665/tb.38.1.012.

Abstract

Spontaneous bacterial peritonitis caused by Vibrio cholerae non-O1/ non-O139 is a rare phenomenon. V. cholerae is known as a common aetiology of epidemic diarrheal disease and rarely causes extra-gastrointestinal infections. In this report, a 52-year-old man presented to our hospital with a clinical scenario for chronic liver cirrhosis with low grade fever and loose stools. V. cholerae was isolated from peritoneal fluid culture, which was further confirmed as non-O1/ non-O139 strain by multiplex polymerase chain reaction. The patient was successfully treated with antimicrobial therapy and peritoneal drainage. This case represents the first isolation of V. cholerae non-O1/ non-O139 strain from peritoneal fluid.

摘要

由霍乱弧菌非 O1/非 O139 引起的自发性细菌性腹膜炎是一种罕见现象。霍乱弧菌是一种常见的流行性腹泻病病原体,很少引起胃肠道外感染。在本报告中,一名 52 岁男性因慢性肝硬化伴低度发热和腹泻就诊。从腹腔液培养中分离出霍乱弧菌,经多重聚合酶链反应进一步证实为非 O1/非 O139 株。患者经抗菌治疗和腹腔引流成功治愈。该病例代表了首例从腹腔液中分离出霍乱弧菌非 O1/非 O139 株。

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