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CT 引导下钝头微波消融电极经皮消融肺磨玻璃密度结节的安全性和有效性研究

Technical safety and efficacy of a blunt-tip microwave ablation electrode for CT-guided ablation of pulmonary ground-glass opacity nodules.

机构信息

Department of Interventional Oncology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, 160# Pujian Road, Shanghai, 200127, China.

出版信息

Eur Radiol. 2021 Oct;31(10):7484-7490. doi: 10.1007/s00330-021-07774-4. Epub 2021 Apr 2.

DOI:10.1007/s00330-021-07774-4
PMID:33797595
Abstract

OBJECTIVES

To evaluate the safety and technical efficacy of a customized blunt-tip microwave ablation (MWA) electrode for CT-guided ablation of pulmonary ground-glass opacity nodules (GGOs).

MATERIALS AND METHODS

This was a retrospective before-after study. All consented patients with GGOs who underwent MWA treatment using conventional sharp-tip electrodes (group A) between January 2018 and December 2018 or new blunt-tip electrodes (group B) between January 2019 and December 2019 in our institution were included. The individual features of each patient and lesion, as well as technical and clinical information, were collected and analyzed.

RESULTS

Sixteen (7 males, 9 females; mean age, 64.9 ± 12.3 years) and twenty-six (11 males, 15 females; mean age, 66.5 ± 10.7 years) patients were enrolled in groups A and B, respectively. The technique was successfully performed in all patients and a follow-up CT scan at 24 h after MWA showed that the technical efficacy rate was 100% in both groups. Twelve (75.0%) grade I complications were noted in group A, whereas 11 (42.3%) were noted in group B (p = 0.039, chi-square test). No bleeding occurred within the lesions in group B.

CONCLUSIONS

The blunt-tip MWA electrode is a safe and technically effective tool for ablating GGO lesions.

KEY POINTS

• A new blunt-tip MWA electrode was used for CT-guided ablation of GGO lesions. • The blunt-tip MWA electrode could improve the safety of GGO ablation. • The technical efficacy of ablation was maintained by using the blunt-tip MWA electrode.

摘要

目的

评估 CT 引导下使用定制钝头微波消融(MWA)电极消融肺磨玻璃密度结节(GGO)的安全性和技术疗效。

材料和方法

这是一项回顾性前后对照研究。所有在我院接受 MWA 治疗的 GGO 患者均纳入本研究,根据消融电极的不同分为两组:使用传统锐头电极(A 组)治疗的患者为 2018 年 1 月至 2018 年 12 月,使用新型钝头电极(B 组)治疗的患者为 2019 年 1 月至 2019 年 12 月。收集并分析每位患者及病变的个体特征、技术和临床资料。

结果

A 组共纳入 16 例(7 例男性,9 例女性;平均年龄 64.9±12.3 岁),B 组共纳入 26 例(11 例男性,15 例女性;平均年龄 66.5±10.7 岁)。所有患者均成功完成消融治疗,术后 24 h 行 CT 扫描,两组技术疗效均为 100%。A 组发生 12 例(75.0%)Ⅰ级并发症,B 组发生 11 例(42.3%)(p=0.039,卡方检验)。B 组的病变内无出血发生。

结论

钝头 MWA 电极是一种安全、有效的 GGO 消融工具。

重点

①使用新型钝头 MWA 电极对 GGO 病变进行 CT 引导下消融。②钝头 MWA 电极可提高 GGO 消融的安全性。③使用钝头 MWA 电极可维持消融的技术疗效。

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