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癫痫的手术治疗。

The surgical treatment of epilepsy.

机构信息

Division of Neurosurgery, IRCCS Giannina Gaslini Children's Hospital, Genoa, Italy.

Epilepsy Surgery Centre, IRCCS Neuromed, Via Atinense, 18, 86170, Pozzilli, IS, Italy.

出版信息

Neurol Sci. 2021 Jun;42(6):2249-2260. doi: 10.1007/s10072-021-05198-y. Epub 2021 Apr 2.

DOI:10.1007/s10072-021-05198-y
PMID:33797619
Abstract

In 2009, the Commission for Epilepsy Surgery of the Italian League Against Epilepsy (LICE) conducted an overview about the techniques used for the pre-surgical evaluation and the surgical treatment of epilepsies. The recognition that, in selected cases, surgery can be considered the first-line approach, suggested that the experience gained by the main Italian referral centers should be pooled in order to provide a handy source of reference. In light of the progress made over these past years, some parts of that first report have accordingly been updated. The present revision aims to harmonize the general principles regulating the patient selection and the pre-surgical work-up, as well as to expand the use of epilepsy surgery, that still represents an underutilized resource, regrettably. The objective of this contribution is drawing up a methodological framework within which to integrate the experiences of each group in this complex and dynamic sector of the neurosciences.

摘要

2009 年,意大利癫痫学会(LICE)癫痫外科委员会对癫痫的术前评估和手术治疗所使用的技术进行了综述。人们认识到,在某些特定情况下,手术可以被视为一线治疗方法,因此,意大利主要转诊中心的经验应该被汇集起来,以便提供一个方便的参考来源。鉴于这些年来所取得的进展,该报告的一些部分进行了相应的更新。本次修订旨在协调规范患者选择和术前评估的一般原则,并扩大癫痫手术的应用,不幸的是,这仍然是一种未充分利用的资源。本研究旨在制定一个方法框架,以便整合每个小组在神经科学这一复杂和动态领域的经验。

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1
The surgical treatment of epilepsy.癫痫的手术治疗。
Neurol Sci. 2021 Jun;42(6):2249-2260. doi: 10.1007/s10072-021-05198-y. Epub 2021 Apr 2.
2
Overview of presurgical assessment and surgical treatment of epilepsy from the Italian League Against Epilepsy.意大利抗癫痫联盟关于癫痫术前评估和手术治疗的概述。
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Trends in pediatric epilepsy surgery.小儿癫痫手术的发展趋势
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Evolution of concepts in epilepsy surgery.癫痫手术理念的演变。
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Epilepsy surgery: guidelines for minimum standard equipment and organization.癫痫手术:最低标准设备与组织指南
J Neurosurg Sci. 2000 Dec;44(4):173-6.
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Should we reconsider epilepsy surgery? The motivation of patients once rejected.我们应该重新考虑癫痫手术吗?患者曾经被拒绝的动机。
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[Children with drug-resistant partial epilepsy: criteria for the identification of surgical candidates].[耐药性部分性癫痫患儿:手术候选者的识别标准]
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Temporal lobe epilepsy surgery in children and adults: A multicenter study.儿童和成人颞叶癫痫手术:一项多中心研究。
Epilepsia. 2021 Jan;62(1):128-142. doi: 10.1111/epi.16772. Epub 2020 Dec 1.
2
Seizure outcome and use of antiepileptic drugs after epilepsy surgery according to histopathological diagnosis: a retrospective multicentre cohort study.根据组织病理学诊断的癫痫手术后癫痫发作结局和抗癫痫药物的使用:一项回顾性多中心队列研究。
Lancet Neurol. 2020 Sep;19(9):748-757. doi: 10.1016/S1474-4422(20)30220-9.
3
Neuromodulation for the Treatment of Epilepsy: A Review of Current Approaches and Future Directions.
癫痫各种治疗策略的现状与进展综述
ACS Pharmacol Transl Sci. 2024 Nov 1;7(12):3729-3757. doi: 10.1021/acsptsci.4c00494. eCollection 2024 Dec 13.
4
Simultaneous F-FDG PET/MRI predicting favourable surgical outcome in refractory epilepsy patients.同时进行的F-FDG PET/MRI预测难治性癫痫患者良好的手术结果。
Neuroradiology. 2025 Jan;67(1):89-97. doi: 10.1007/s00234-024-03446-4. Epub 2024 Aug 22.
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The Purinergic P2X7 Receptor as a Target for Adjunctive Treatment for Drug-Refractory Epilepsy.嘌呤能 P2X7 受体作为辅助治疗耐药性癫痫的靶点。
Int J Mol Sci. 2024 Jun 23;25(13):6894. doi: 10.3390/ijms25136894.
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Epilepsia Open. 2024 Aug;9(4):1382-1392. doi: 10.1002/epi4.12965. Epub 2024 Jun 19.
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