Biostatistics and Bioinformatics (DIM), Dijon University Hospital, Dijon, France.
University of Burgundy and Franche-Comte, Dijon, France.
Diabet Med. 2021 Jul;38(7):e14577. doi: 10.1111/dme.14577. Epub 2021 Apr 13.
AIMS/HYPOTHESIS: The aim of this study was to examine the impact of the COVID-19 epidemic on the hospitalization rates for diabetic foot ulcer (DFU), osteomyelitis and lower limb revascularization procedure in people with DFU.
This nationwide retrospective cohort study included hospital data on all people hospitalized in France for diabetes in weeks 2-43 in 2020, including the COVID-19 lockdown period, compared to same period in 2019.
The number of hospitalizations for DFU decreased significantly in weeks 12-19 (during the lockdown) (p < 10 ). Hospitalization for foot osteomyelitis also decreased significantly in weeks 12-19 (p < 10 ). The trend was the same for lower limb amputations and revascularizations associated with DFU or amputation.
CONCLUSIONS/INTERPRETATION: The marked drop in hospitalization rates for DFU, osteomyelitis and lower limb revascularization procedures in people with DFU observed in France during the lockdown period suggests that COVID-19 was a barrier to DFU care, and may illustrate the combined deleterious effects of hospital overload and changes in health-related behaviour.
目的/假设：本研究旨在探讨 COVID-19 疫情对糖尿病足溃疡（DFU）、骨髓炎和下肢血运重建手术住院率的影响。
这是一项全国性回顾性队列研究，纳入了 2020 年第 2 周至第 43 周期间所有在法国因糖尿病住院的患者的医院数据，包括 COVID-19 封锁期间的数据，与 2019 年同期进行比较。
在封锁期间的第 12-19 周（p<0.01），DFU 的住院人数显著下降。足部骨髓炎的住院人数也在第 12-19 周显著下降（p<0.01）。与 DFU 或截肢相关的下肢截肢和血运重建的趋势也是如此。
结论/解释：在法国封锁期间，DFU、骨髓炎和下肢血运重建手术的住院率显著下降，表明 COVID-19 是 DFU 治疗的障碍，可能说明了医院过载和健康相关行为变化的综合有害影响。
