Department of Orthopedic Surgery, UZ Leuven, Herestraat 49, Leuven, Belgium.
Department of Orthopedic Surgery, UZ Leuven, Herestraat 49, Leuven, Belgium.
Hand Surg Rehabil. 2021 Sep;40(4):495-499. doi: 10.1016/j.hansur.2021.03.008. Epub 2021 Mar 30.
Full thickness grafting can be considered after fasciectomy for Dupuytren contracture in severe cases with skin shortage or in radical dermofasciectomy. It is a common dogma that these skin grafts may prevent disease recurrence. We reviewed 47 patients after fasciectomy and full-thickness skin grafting for Dupuytren contracture at 3-16 years' follow-up. Recurrence beneath the skin graft and extension of the disease in the rest of the hand were recorded. Age at onset, gender and factors considered to influence the outcome due to fibrosis diathesis, such as bilateral disease, family history and ectopic lesions, were noted. The Tubiana classification was used to grade disease severity at surgery and at follow-up. None of the patients manifested recurrence underneath the skin graft, but the disease did show extension in 83% of cases. Disease extension was more likely in patients with higher fibrosis diathesis scores. We conclude that skin grafting may prevent disease recurrence underneath the grafts, but extension of the disease correlates with fibrosis diathesis. LEVEL OF EVIDENCE: IV, therapeutic cohort study.
在严重的掌腱膜挛缩症病例中,如果存在皮肤短缺或根治性皮肤筋膜切除术,可考虑进行全厚皮片移植。一个常见的观点是,这些皮片可以预防疾病复发。我们回顾了 47 例接受掌腱膜挛缩症切开松解和全厚皮片移植的患者,随访时间为 3 至 16 年。记录了皮片下的复发和手部其余部位疾病的进展情况。记录了发病年龄、性别以及纤维化素质等可能影响预后的因素,如双侧疾病、家族史和异位病变。采用 Tubiana 分类法对手术时和随访时的疾病严重程度进行分级。没有患者在皮片下出现复发,但在 83%的病例中确实出现了疾病进展。纤维化素质评分较高的患者更有可能出现疾病进展。我们的结论是,皮片移植可以预防皮片下的疾病复发,但疾病的进展与纤维化素质有关。证据等级:IV,治疗性队列研究。