Department of Clinical Psychology and Psychotherapy, University of Koblenz-Landau, Germany.
Department of Clinical Psychology and Psychotherapy, University of Koblenz-Landau, Germany.
Psychiatry Res. 2021 Jun;300:113895. doi: 10.1016/j.psychres.2021.113895. Epub 2021 Mar 23.
The aim of the study was to investigate changes in both subjectively and objectively measured cognitive functions as well as their discrepancy in outpatients with major depression disorder in the course of cognitive-behavioural therapy (CBT). A neuropsychological test battery with cognitive tests measuring the domains of attention, memory, and executive functions as well as a questionnaire for the self-assessment of cognitive functions (FLei) in these domains were administered to depressed outpatients (n = 46) at the beginning of CBT, post-treatment after on average 40 sessions, as well as six months after the end of treatment. We found that subjectively as well as objectively measured cognitive functions did not change. The discrepancy between subjective and objective cognitive functions found at the beginning of therapy was no longer significant at post-treatment and six months later. The results indicate, that self-perceived and neuropsychologically measured cognitive impairments show stability despite improved depression. Specific interventions such as cognitive remediation therapy should be additionally applied to depressed patients who suffer from cognitive deficits.
本研究旨在探讨认知行为疗法(CBT)过程中,重度抑郁症患者的主观和客观认知功能的变化及其差异。在 CBT 开始时,对抑郁门诊患者(n=46)进行了神经心理测试,包括注意力、记忆和执行功能等认知测试,以及用于自我评估这些领域认知功能的问卷(FLei)。在平均 40 次治疗后进行了治疗后评估,以及治疗结束后六个月进行了随访评估。我们发现,无论是主观还是客观的认知功能都没有变化。治疗开始时发现的主观和客观认知功能之间的差异在治疗后和六个月后不再显著。研究结果表明,尽管抑郁得到改善,但自我感知和神经心理测量的认知障碍仍保持稳定。对于存在认知缺陷的抑郁患者,应额外应用特定干预措施,如认知矫正治疗。