Jones A W
Department of Alcohol Toxicology, University Hospital, Linköping, Sweden.
J Anal Toxicol. 1988 Mar-Apr;12(2):75-9. doi: 10.1093/jat/12.2.75.
This paper reports the concentration of acetone in end-expired breath of male volunteers as determined by gas chromatography. It also explores the effect of small doses of ethanol, given orally and intravenously, on breath acetone concentrations and their variations with time after intake. When subjects drank a small dose of alcohol (0.25 g/kg) after 12 h fasting, their breath acetone concentration decreased abruptly by 40%. The breath acetone time profile was almost a mirror image of the blood ethanol time course. After 36 h without food, the ethanol-induced drop in breath acetone was 18%. Ethanol given intravenously likewise caused a significant lowering of breath acetone concentration.
本文报告了通过气相色谱法测定的男性志愿者终末呼气中丙酮的浓度。它还探讨了口服和静脉注射小剂量乙醇对呼气丙酮浓度及其摄入后随时间变化的影响。当受试者在禁食12小时后饮用小剂量酒精（0.25 g/kg）时，他们的呼气丙酮浓度突然下降了40%。呼气丙酮时间曲线几乎是血液乙醇时间进程的镜像。在禁食36小时后，乙醇引起的呼气丙酮下降为18%。静脉注射乙醇同样导致呼气丙酮浓度显著降低。
