Razmeh Saeed, Niknam Nafiseh, Sadat Rabbani Negar, Nikoee Shekoofeh, Vafa Pour Fatemeh, Taghavian Laleh
Department of Neurology, Shahid Beheshti Hospital, Yasuj University of Medical Sciences, Yasuj 75914-93686, Iran.
Student Research Committee, Yasuj University of Medical Sciences, Yasuj 75914-93686, Iran.
Neurol Int. 2021 Mar 11;13(1):120-124. doi: 10.3390/neurolint13010011.
Inflammatory bowel disease (IBD) including ulcerative colitis and Crohn's disease puts patients at high risk of thromboembolism accidents. These patients may take infliximab for active and fistulating Crohn's disease, which can also increase the risk of thrombosis. Deep vein thrombosis (DVT) and pulmonary thromboembolism (PTE) are more common among these patients, but cerebrovascular, mesenteric, portal and retinal veins can also be affected. In this paper, we report a case of isolated right Labbe vein thrombosis after infliximab therapy for Crohn's disease. To the best of our knowledge, our patient is the first case report of isolated cortical vein thrombosis following administration of rituximab for Crohn's disease.
炎症性肠病（IBD），包括溃疡性结肠炎和克罗恩病，使患者面临血栓栓塞事件的高风险。这些患者可能会使用英夫利昔单抗治疗活动性及瘘管性克罗恩病，这也会增加血栓形成的风险。深静脉血栓形成（DVT）和肺血栓栓塞（PTE）在这些患者中更为常见，但脑血管、肠系膜、门静脉和视网膜静脉也可能受到影响。在本文中，我们报告了一例在使用英夫利昔单抗治疗克罗恩病后发生孤立性右侧Labbe静脉血栓形成的病例。据我们所知，我们的患者是首例使用英夫利昔单抗治疗克罗恩病后发生孤立性皮质静脉血栓形成的病例报告。
