马铃薯 X 病毒感染早期相关的转录调控网络。

Transcriptional Regulatory Networks Associate with Early Stages of Potato Virus X Infection of .

机构信息

Department of Plant Pathology and Microbiology, Texas A&M University, College Station, TX 77802, USA.

Department of Agriculture Biology, Faculty of Agriculture, University of Peradeniya, Peradeniya 20400, Sri Lanka.

出版信息

Int J Mol Sci. 2021 Mar 11;22(6):2837. doi: 10.3390/ijms22062837.

(PVX) belongs to genus This study characterizes the cellular transcriptome responses to PVX infection in Russet potato at 2 and 3 days post infection (dpi). Among the 1242 differentially expressed genes (DEGs), 268 genes were upregulated, and 37 genes were downregulated at 2 dpi while 677 genes were upregulated, and 265 genes were downregulated at 3 dpi. DEGs related to signal transduction, stress response, and redox processes. Key stress related transcription factors were identified. Twenty-five pathogen resistance gene analogs linked to effector triggered immunity or pathogen-associated molecular pattern (PAMP)-triggered immunity were identified. Comparative analysis with Arabidopsis unfolded protein response (UPR) induced DEGs revealed genes associated with UPR and plasmodesmata transport that are likely needed to establish infection. In conclusion, this study provides an insight on major transcriptional regulatory networked involved in early response to PVX infection and establishment.

(PVX) 属于 This study characterizes the cellular transcriptome responses to PVX infection in Russet potato at 2 and 3 days post infection (dpi). Among the 1242 differentially expressed genes (DEGs), 268 genes were upregulated, and 37 genes were downregulated at 2 dpi while 677 genes were upregulated, and 265 genes were downregulated at 3 dpi. DEGs related to signal transduction, stress response, and redox processes. Key stress related transcription factors were identified. Twenty-five pathogen resistance gene analogs linked to effector triggered immunity or pathogen-associated molecular pattern (PAMP)-triggered immunity were identified. Comparative analysis with Arabidopsis unfolded protein response (UPR) induced DEGs revealed genes associated with UPR and plasmodesmata transport that are likely needed to establish infection. In conclusion, this study provides an insight on major transcriptional regulatory networked involved in early response to PVX infection and establishment.

(PVX) 属于马铃薯卷叶病毒属。本研究在感染后 2 和 3 天（dpi），对 Russet 马铃薯感染 PVX 后的细胞转录组应答进行了特征描述。在 1242 个差异表达基因（DEGs）中，有 268 个基因在 2dpi 时上调，37 个基因下调，而在 3dpi 时有 677 个基因上调，265 个基因下调。与信号转导、应激反应和氧化还原过程相关的 DEGs。鉴定出与效应子触发免疫或病原体相关分子模式（PAMP）触发免疫相关的 25 个抗病基因类似物。与拟南芥未折叠蛋白反应（UPR）诱导的 DEGs 的比较分析表明，与 UPR 和胞间连丝运输相关的基因可能是建立感染所必需的。总之，本研究为早期对 PVX 感染和建立的主要转录调控网络提供了深入了解。