Cobb C J
Department of Pathology, Harbor-UCLA Medical Center, Torrance 90509.
J Surg Oncol. 1988 Jun;38(2):126-9. doi: 10.1002/jso.2930380215.
The presence of ectopic decidua in pelvic lymph nodes from patients with squamous carcinoma of the cervix makes evaluation for metastatic disease difficult due to the light microscopic similarity between decidua and sheets of squamous epithelial cells. A patient is present in whom decidualized endometriosis was intimately associated with metastatic moderately differentiate squamous carcinoma in a single pelvic lymph node. This phenomenon afforded an excellent opportunity to study the unique morphologic features that distinguish these two entities. A prior report of this kind was not found. In the absence of obvious squamous differentiation (i.e., intercellular bridges, dyskeratosis, and keratin "pearl" formation), as is frequently the case with squamous carcinoma of the cervix, the light microscopic features that are most useful in distinguishing squamous carcinoma from decidua include the presence of well-defined nests of cohesive cells, nuclear hyperchromasia, and cellular pleomorphism.
由于蜕膜与鳞状上皮细胞片层在光镜下相似，子宫颈鳞状细胞癌患者盆腔淋巴结中存在异位蜕膜会使转移性疾病的评估变得困难。有一名患者，其蜕膜化子宫内膜与单个盆腔淋巴结中的转移性中度分化鳞状细胞癌密切相关。这种现象为研究区分这两种实体的独特形态学特征提供了绝佳机会。未发现此类先前报告。在没有明显鳞状分化（即细胞间桥、异常角化和角质“珠”形成）的情况下，这在子宫颈鳞状细胞癌中很常见，光镜下区分鳞状细胞癌与蜕膜最有用的特征包括存在界限清楚的紧密细胞巢、核深染和细胞多形性。
