Schwegler H, Heimrich B, Keller F, Renner P, Crusio W E
Institut für Humangenetik and Anthropologie, Universität Heidelberg, F.R.G.
Neurosci Lett. 1988 Apr 22;87(1-2):7-10. doi: 10.1016/0304-3940(88)90136-x.
The postnatal development of the hippocampus of the inbred mice strains BALB/c, C57BL/6, and DBA/2 was studied in organotypic explant cultures using the roller-tube technique. In vivo, mice exhibit strain-specific mossy fiber distribution patterns. As a main result we found, that after cultivation of 3-4 weeks, similar strain-specific patterns became apparent in vitro, as visualized by a modified Timm staining. From this experiment we can conclude that a postnatal extrinsic influence cannot be the cause of the strain-specific hippocampal features.
利用滚管技术，在器官型外植体培养中研究了近交系小鼠品系BALB/c、C57BL/6和DBA/2海马的出生后发育。在体内，小鼠表现出品系特异性的苔藓纤维分布模式。作为主要结果，我们发现，在培养3-4周后，通过改良的Timm染色可见，体外出现了类似的品系特异性模式。从这个实验我们可以得出结论，出生后的外在影响不可能是品系特异性海马特征的原因。
