Heimrich B, Claus H, Schwegler H, Haas H L
Physiologisches Institut, Universität Mainz, F.R.G.
Brain Res. 1989 Jun 26;490(2):404-6. doi: 10.1016/0006-8993(89)90262-x.
We studied long-term potentiation in the inbred mouse strains DBA/2 and C3H/He known to be different in both hippocampal mossy fiber distribution and several aspects of learning. Tetanic stimulation of mossy fibers resulted in a significantly stronger increase of the population spike amplitude in the CA3 pyramidal cell layer of C3H mice. This result suggests that the extent of the CA3 hippocampal mossy fiber projection correlates with synaptic efficacy in mice.
我们研究了近交系小鼠品系DBA/2和C3H/He中的长时程增强效应，已知这两个品系在海马苔藓纤维分布和学习的几个方面存在差异。对苔藓纤维进行强直刺激后，C3H小鼠CA3锥体细胞层群体峰电位幅度的增加明显更强。这一结果表明，海马CA3区苔藓纤维投射的程度与小鼠的突触效能相关。
