Barkhudaryan Anush, Doehner Wolfram, Scherbakov Nadja
Department of Cardiology, Clinic of General and Invasive Cardiology, University Hospital No 1, Yerevan State Medical University, Yerevan 0025, Armenia.
Cardiovascular Research Institute Basel, University Hospital Basel, 4056 Basel, Switzerland.
J Clin Med. 2021 Mar 9;10(5):1146. doi: 10.3390/jcm10051146.
Heart failure (HF) is a severe clinical syndrome accompanied by a number of comorbidities. Ischemic stroke occurs frequently in patients with HF as a complication of the disease. In the present review, we aimed to summarize the current state of research on the role of cardio-cerebral interactions in the prevalence, etiology, and prognosis of both diseases. The main pathophysiological mechanisms underlying the development of stroke in HF and vice versa are discussed. In addition, we reviewed the results of recent clinical trials investigating the prevalence and prevention of stroke in patients with HF.
心力衰竭(HF)是一种伴有多种合并症的严重临床综合征。缺血性中风作为HF的并发症,在HF患者中频繁发生。在本综述中,我们旨在总结关于心脑相互作用在这两种疾病的患病率、病因和预后中的作用的当前研究现状。讨论了HF中中风发生以及反之亦然的主要病理生理机制。此外,我们回顾了近期关于HF患者中风患病率及预防的临床试验结果。