Meckler R L, Weaver L C
Department of Physiology, Michigan State University, East Lansing 48824-1101.
Neurosci Lett. 1988 May 26;88(2):167-72. doi: 10.1016/0304-3940(88)90120-6.
Experiments were done to evaluate the contribution of peripheral neural circuits to generation of ongoing splenic and renal sympathetic discharge as well as to the reflex alteration of this discharge by chemical stimulation of receptors of intestinal afferent nerves. After decentralization of the celiac and superior mesenteric ganglia, low amplitude spikes with low discharge rates still were observed in both nerves. Stimulation of intestinal receptors with bradykinin or capsaicin did not alter this residual firing. Cholinergic blockade eliminated most of this discharge. The source of the residual firing and its contribution to basal discharge of splenic and renal nerves remains to be determined.
进行实验以评估外周神经回路对持续性脾和肾交感神经放电的产生以及通过化学刺激肠传入神经受体对该放电的反射性改变的贡献。在腹腔神经节和肠系膜上神经节去神经支配后，仍在两条神经中观察到放电率低的低幅度尖峰。用缓激肽或辣椒素刺激肠受体并没有改变这种残余放电。胆碱能阻断消除了大部分这种放电。残余放电的来源及其对脾神经和肾神经基础放电的贡献仍有待确定。
