Demidov Lev, Samoylenko Igor, Vand Nina, Utyashev Igor, Shubina Irina, Sinelnikov Igor
FSBI N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia, Moscow 115548, Russia.
Russian Melanoma Professional Association (Melanoma.PRO), Moscow 119192, Russia.
Dermatopathology (Basel). 2021 Mar 15;8(1):54-68. doi: 10.3390/dermatopathology8010011.
The screening program Life Fear-Free (LFF) aimed at early diagnosis of cutaneous melanoma (CM) was introduced in Samara, Chelyabinsk, Yekaterinburg, and Krasnodar (Russia) in 2019.
To analyze the impact of the program on early CM and non-melanoma skin cancer (NMSC) detection.
According to the social educational campaign, people were informed about CM risk factors and symptoms and were invited for skin examination. The program planned to involve 3200 participants in total. Participants with suspicious lesions were invited for excisional biopsy.
3143 participants, including 75.4% women, were examined for skin lesions. The average age of the participants was 43.7 years. Mostly skin phototypes II and III were registered (48.2% and 41.0%, respectively); 3 patients had CM, 15 had basal cell carcinoma, and 1 had Bowen's disease, which were confirmed histologically. All detected melanomas had Breslow's thickness of 1 mm.
The participants showed high interest in early skin cancer detection programs. The incidence rate of CM and NMSCs among the program participants was higher than in general public. The early disease grade was proven for the detected CMs and NMSCs. The study has shown that it is important to continue such programs.
2019年，“无惧生命恐惧”（LFF）皮肤癌筛查项目在俄罗斯的萨马拉、车里雅宾斯克、叶卡捷琳堡和克拉斯诺达尔启动，旨在早期诊断皮肤黑色素瘤（CM）。
分析该项目对早期CM和非黑色素瘤皮肤癌（NMSC）检测的影响。
根据社会教育活动，向人们宣传CM的危险因素和症状，并邀请他们进行皮肤检查。该项目计划共纳入3200名参与者。有可疑病变的参与者被邀请进行切除活检。
共对3143名参与者进行了皮肤病变检查，其中女性占75.4%。参与者的平均年龄为43.7岁。登记的皮肤光类型主要为II型和III型（分别为48.2%和41.0%）；3例为CM，15例为基底细胞癌，1例为鲍温病，均经组织学证实。所有检测到的黑色素瘤的 Breslow 厚度均为1 mm。
参与者对早期皮肤癌检测项目表现出高度兴趣。该项目参与者中CM和NMSC的发病率高于普通人群。检测到的CM和NMSC均为早期疾病阶段。研究表明，继续开展此类项目很重要。
