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COVID-19 大流行对免疫性血小板减少症患者的影响。

Impact of COVID-19 Pandemic on Patients with Immune Thrombocytopaenia.

机构信息

Hematology Unit, La Paz University Hospital-IdiPAZ, Paseo de la Castellana 261, Hospital Universitario La Paz, 28046 Madrid, Spain.

Medicine Department, Autonomous University of Madrid, Arzobispo Morcillo 4, 28029 Madrid, Spain.

出版信息

Medicina (Kaunas). 2021 Mar 1;57(3):219. doi: 10.3390/medicina57030219.

Abstract

: The aim of this study was to determine the impact of the COVID-19 pandemic on the lives of patients with immune thrombocytopaenia (ITP) treated at our hospital. : The study was conducted in the Community of Madrid, which has the highest number of COVID-19 cases in Spain. We included 143 adult patients with ITP (130 with chronic ITP, 8 with persistent ITP, and 5 with newly diagnosed ITP). We conducted a telephone survey to collect the data and created a registry. : Overall, 24 patients presented symptoms suggestive of COVID-19, which was confirmed by RT-PCR in 8 cases. The cumulative incidence of confirmed SARS-CoV-2 infection was higher in the patients with ITP than in the Madrid population. There were no differences in the disease incidence or clinical course of infection in the patients treated with immunosuppressants. Almost all of the patients reported adherence to the prescribed treatment, although 49.2% of the hospital visits were either cancelled or postponed, 17.2% because of the patients' fear of coming to the centre. Nearly half of the cohort was considered vulnerable, and 17% had been granted a dependency or disability benefit. : COVID-19 had a major impact on the psychosocial, occupational, and quality of care of patients with ITP.

摘要

本研究旨在确定 COVID-19 大流行对在我院接受治疗的免疫性血小板减少症 (ITP) 患者生活的影响。

该研究在马德里社区进行,马德里是西班牙 COVID-19 病例最多的地区。我们纳入了 143 例成年 ITP 患者(130 例慢性 ITP,8 例持续性 ITP,5 例新诊断的 ITP)。我们通过电话调查收集数据并建立了一个登记册。

总体而言,24 例患者出现了 COVID-19 的症状,其中 8 例经 RT-PCR 确诊。与马德里人群相比,接受免疫抑制剂治疗的患者的 SARS-CoV-2 感染确诊累积发病率更高。在接受免疫抑制剂治疗的患者中,疾病发病率或感染的临床过程无差异。尽管 49.2%的医院就诊被取消或推迟,17.2%是因为患者担心来中心,几乎所有患者都报告了对规定治疗的依从性,但有 17.2%的患者因担心来中心而取消或推迟了就诊。近一半的患者被认为是脆弱的,17%的患者获得了依赖或残疾津贴。

COVID-19 对 ITP 患者的社会心理、职业和护理质量产生了重大影响。

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