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梅-图二氏综合征在孕期会加重。

May-Thurner Syndrome Is Aggravated by Pregnancy.

作者信息

Traisrisilp Kuntharee, Manopunya Manatsawee, Srisuwan Tanop, Chankhunaphas Wisit, Tongsong Theera

机构信息

Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.

出版信息

Medicina (Kaunas). 2021 Mar 1;57(3):222. doi: 10.3390/medicina57030222.

DOI:10.3390/medicina57030222
PMID:33804526
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7999580/
Abstract

This study aims to emphasize that asymptomatic patients with undiagnosed and asymptomatic May-Thurner syndrome (MTS) may firstly develop severe compression during pregnancy. A 40-year-old woman, G1P0, at 22 weeks of twin gestation presented with left lower extremity edema and pain. One twin was structurally normal while the other had bilateral renal agenesis with oligohydramnios. Magnetic resonance venography (MRV) revealed severe compression of the left iliac vein by the right iliac artery without evidence of deep vein thrombosis (DVT). Conservative treatment with anticoagulant prophylaxis was instituted throughout the rest of pregnancy and postpartum period. She was also complicated with severe pre-eclampsia, a cesarean section was performed due to a prolapsed cord at 27 weeks of gestation, and she gave birth to a surviving baby weighing 1100 g. In conclusion, this case report provides evidence that pregnancy can disclose a subtle May-Thurner anatomy to be symptomatic without DVT. Successful pregnancy outcomes could be achieved with conservative treatment and anticoagulant prophylaxis.

摘要

本研究旨在强调,未诊断出且无症状的梅-图二氏综合征(MTS)的无症状患者在孕期可能首先出现严重压迫症状。一名40岁女性,孕1产0,双胎妊娠22周时出现左下肢水肿和疼痛。其中一个胎儿结构正常,另一个胎儿双侧肾缺如并羊水过少。磁共振静脉造影(MRV)显示右髂动脉严重压迫左髂静脉,无深静脉血栓形成(DVT)证据。在整个孕期剩余时间及产后均采用抗凝预防的保守治疗。她还并发了严重子痫前期,因孕27周时脐带脱垂行剖宫产,产下一名体重1100g的存活婴儿。总之,本病例报告证明,妊娠可使隐匿的梅-图二氏解剖结构出现症状,且无DVT。采用保守治疗和抗凝预防可实现成功的妊娠结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e11e/7999580/c53d3170ae93/medicina-57-00222-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e11e/7999580/b15b58e625c6/medicina-57-00222-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e11e/7999580/c53d3170ae93/medicina-57-00222-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e11e/7999580/b15b58e625c6/medicina-57-00222-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e11e/7999580/c53d3170ae93/medicina-57-00222-g002.jpg

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本文引用的文献

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May-Thurner Syndrome: A Cause of Acute Left Iliac Vein Obstruction in Early Postpartum Period: A Case Report.梅-图二氏综合征:产后早期急性左髂静脉梗阻的一个病因:病例报告
J Pak Med Assoc. 2019 Jul;69(7):1044-1048.
2
May-Thurner syndrome - Are we aware enough?梅-图二氏综合征——我们对此了解够多了吗?
Vasa. 2019 Aug;48(5):381-388. doi: 10.1024/0301-1526/a000775. Epub 2019 Feb 20.
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Phlegmasia Cerulea Dolens and May-Thurner Syndrome in the first trimester of Pregnancy.妊娠早期的股青肿和May-Thurner综合征
AJP Rep. 2016 Mar;6(1):e71-3. doi: 10.1055/s-0035-1566250. Epub 2015 Nov 16.
4
Anticoagulant Therapy in a Pregnant Woman with May-Thurner Syndrome.一名患有May-Thurner综合征孕妇的抗凝治疗
Intern Med. 2016;55(1):59-62. doi: 10.2169/internalmedicine.55.5215. Epub 2016 Jan 1.
5
Diagnosis and management of iliac vein thrombosis in pregnancy resulting from May-Thurner Syndrome.May-Thurner综合征所致妊娠期髂静脉血栓形成的诊断与管理
J Perinatol. 2014 Jul;34(7):566-8. doi: 10.1038/jp.2014.38.
6
May-Thurner syndrome complicating pregnancy: a report of four cases.合并妊娠的梅-图二氏综合征:四例报告
J Reprod Med. 2014 May-Jun;59(5-6):333-6.
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May-Thurner syndrome resulting in acute iliofemoral deep vein thrombosis during the second trimester of pregnancy.梅-图二氏综合征导致妊娠中期急性髂股深静脉血栓形成。
J Obstet Gynaecol Res. 2012 Aug;38(8):1106-10. doi: 10.1111/j.1447-0756.2011.01840.x. Epub 2012 Apr 30.
8
Computed tomography findings in 10 cases of iliac vein compression (May-Thurner) syndrome.10例髂静脉受压(May-Thurner)综合征的计算机断层扫描结果
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9
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10
Cerebral infarction in conjunction with patent foramen ovale and May-Thurner syndrome.脑梗死合并卵圆孔未闭和梅-图二氏综合征。
J Neuroimaging. 2001 Oct;11(4):432-4. doi: 10.1111/j.1552-6569.2001.tb00074.x.