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一名20岁女性,患有与May-Thurner综合征相关的肺栓塞和深静脉血栓形成。

A 20-year-old woman with pulmonary embolism and deep vein thrombosis associated with May-Thurner syndrome.

作者信息

Yamazaki Yusuke, Ikura Hidehiko, Egashira Toru, Kageyama Toshimi, Shibata Masaru, Moritani Kazunori, Mitamura Hideo

机构信息

Department of Cardiology, Tachikawa Hospital, Tokyo, Japan.

出版信息

Radiol Case Rep. 2025 Jun 5;20(9):4203-4208. doi: 10.1016/j.radcr.2025.05.008. eCollection 2025 Sep.

DOI:10.1016/j.radcr.2025.05.008
PMID:40528922
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12171555/
Abstract

May-Thurner syndrome (MTS) is a clinical condition characterized by the compression of the left common iliac vein between the overlying right common iliac artery and the underlying lumbar vertebrae. Although MTS can lead to deep vein thrombosis (DVT) and, in some cases, pulmonary embolism (PE), it remains underrecognized in clinical practice. We present a case of PE and DVT associated with MTS in a 20-year-old woman with a prolonged history of taking oral contraceptives (OCs). Initial computed tomography angiography (CTA) raised suspicion of MTS, which was further confirmed by Duplex ultrasonography. Anticoagulation therapy, along with discontinuation of OCs, resulted in resolution of thrombi in both the pulmonary and deep venous systems, with no recurrence following cessation of anticoagulation. This case underscores the importance of combining multiple imaging modalities in the evaluation of young women presenting with left-sided DVT, which eventually led to the diagnosis and proper management of MTS.

摘要

梅-图二氏综合征(MTS)是一种临床病症,其特征为左髂总静脉受到上方的右髂总动脉和下方的腰椎压迫。尽管MTS可导致深静脉血栓形成(DVT),在某些情况下还会引发肺栓塞(PE),但在临床实践中它仍未得到充分认识。我们报告一例20岁长期服用口服避孕药(OC)的女性患者发生与MTS相关的PE和DVT的病例。最初的计算机断层扫描血管造影(CTA)引发了对MTS的怀疑,双功超声进一步证实了这一诊断。抗凝治疗以及停用OC导致肺和深静脉系统中的血栓溶解,抗凝治疗停止后未出现复发。该病例强调了在评估出现左侧DVT的年轻女性时结合多种成像方式的重要性,这最终促成了MTS的诊断和恰当治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89a5/12171555/fbeb5d5752dc/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89a5/12171555/13588304a7f4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89a5/12171555/65c9642eb81d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89a5/12171555/fbeb5d5752dc/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89a5/12171555/13588304a7f4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89a5/12171555/65c9642eb81d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89a5/12171555/fbeb5d5752dc/gr3.jpg

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本文引用的文献

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May-Thurner Syndrome: An Interesting Presentation of Recurrent, Unprovoked Deep Vein Thrombosis.梅-图二氏综合征:复发性、自发性深静脉血栓形成的一种有趣表现
Cureus. 2023 Aug 14;15(8):e43491. doi: 10.7759/cureus.43491. eCollection 2023 Aug.
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Prevalence and predictors of radiological left common iliac vein compression in asymptomatic patients.无症状患者中放射学左侧髂总静脉压迫的流行率及预测因素。
J Vasc Surg Venous Lymphat Disord. 2024 Jan;12(1):101661. doi: 10.1016/j.jvsv.2023.07.011. Epub 2023 Aug 10.
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May-Thurner Syndrome-a Rare Cause of Extensive Pelvic DVT, but Is there More to Know?
梅-图二氏综合征——广泛盆腔深静脉血栓形成的罕见病因,但还有更多有待了解之处吗?
Case Rep Vasc Med. 2022 Oct 25;2022:7978470. doi: 10.1155/2022/7978470. eCollection 2022.
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May-Thurner syndrome.梅-图二氏综合征
Cardiovasc Diagn Ther. 2021 Oct;11(5):1104-1111. doi: 10.21037/cdt.2020.03.07.
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Contemporary treatment of May-Thurner Syndrome.梅-图二氏综合征的现代治疗方法。
J Cardiovasc Surg (Torino). 2021 Oct;62(5):447-455. doi: 10.23736/S0021-9509.21.11889-0. Epub 2021 Apr 19.
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May-Thurner Syndrome Is Aggravated by Pregnancy.梅-图二氏综合征在孕期会加重。
Medicina (Kaunas). 2021 Mar 1;57(3):222. doi: 10.3390/medicina57030222.
7
May-Thurner syndrome: History of understanding and need for defining population prevalence.梅-图二氏综合征:认识历程与界定人群患病率的必要性
J Thromb Haemost. 2020 Mar;18(3):534-542. doi: 10.1111/jth.14707. Epub 2019 Dec 27.
8
Systematic review of May-Thurner syndrome with emphasis on gender differences.对梅-特纳综合征的系统评价,重点关注性别差异。
J Vasc Surg Venous Lymphat Disord. 2018 May;6(3):399-407.e4. doi: 10.1016/j.jvsv.2017.11.006. Epub 2017 Dec 28.
9
Apixaban for the Treatment of Japanese Subjects With Acute Venous Thromboembolism (AMPLIFY-J Study).阿哌沙班治疗日本急性静脉血栓栓塞症患者(AMPLIFY-J研究)。
Circ J. 2015;79(6):1230-6. doi: 10.1253/circj.CJ-15-0195. Epub 2015 Apr 24.
10
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