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The Potential Role of Nonhuman Primate Models to Better Comprehend Early Life Immunity and Maternal Antibody Transfer.非人灵长类动物模型在更好理解早期生命免疫和母体抗体转移方面的潜在作用。
Vaccines (Basel). 2021 Mar 24;9(4):306. doi: 10.3390/vaccines9040306.
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Predictive value of primate models for AIDS.灵长类动物模型对艾滋病的预测价值。
AIDS Rev. 2004 Oct-Dec;6(4):187-98.
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Influence of maternal antibodies on vaccine responses: inhibition of antibody but not T cell responses allows successful early prime-boost strategies in mice.母源抗体对疫苗应答的影响：抑制抗体而非T细胞应答可使小鼠早期初免-加强策略成功实施。
Eur J Immunol. 1998 Dec;28(12):4138-48. doi: 10.1002/(SICI)1521-4141(199812)28:12<4138::AID-IMMU4138>3.0.CO;2-L.
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Protective immunity against respiratory syncytial virus in early life after murine maternal or neonatal vaccination with the recombinant G fusion protein BBG2Na.用重组G融合蛋白BBG2Na对小鼠进行母体或新生期疫苗接种后，早期对呼吸道合胞病毒的保护性免疫。
J Infect Dis. 1997 Oct;176(4):884-91. doi: 10.1086/516503.
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Maternal immunity and infant responses to immunization: factors influencing infant responses.母体免疫与婴儿对免疫接种的反应：影响婴儿反应的因素
Dev Biol Stand. 1998;95:133-9.
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Prospects for vaccines during pregnancy and in the newborn period.孕期及新生儿期疫苗的前景。
Clin Perinatol. 1997 Mar;24(1):231-49.
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Pertussis Maternal Immunization: Narrowing the Knowledge Gaps on the Duration of Transferred Protective Immunity and on Vaccination Frequency.百日咳母体免疫：缩小关于转移的保护性免疫持续时间和疫苗接种频率的知识差距。
Front Immunol. 2017 Sep 6;8:1099. doi: 10.3389/fimmu.2017.01099. eCollection 2017.
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AIDS Vaccine Research Subcommittee (AVRS) Consultation: Early-Life Immunization Strategies against HIV Acquisition.艾滋病疫苗研究小组委员会（AVRS）咨询：针对 HIV 获得的婴幼儿免疫策略。
mSphere. 2019 Jul 17;4(4):e00320-19. doi: 10.1128/mSphere.00320-19.
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HIV Env-Specific IgG Antibodies Induced by Vaccination of Neonatal Rhesus Macaques Persist and Can Be Augmented by a Late Booster Immunization in Infancy.接种疫苗可诱导新生恒河猴产生 HIV Env 特异性 IgG 抗体，并可在婴儿期通过晚期加强免疫来增强。
mSphere. 2020 Mar 25;5(2):e00162-20. doi: 10.1128/mSphere.00162-20.
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Maternal antibodies and infant immune responses to vaccines.母体抗体与婴儿对疫苗的免疫反应。
Vaccine. 2015 Nov 25;33(47):6469-72. doi: 10.1016/j.vaccine.2015.07.085. Epub 2015 Aug 6.
引用本文的文献
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Nonhuman primate models of pediatric viral diseases.儿科病毒性疾病的非人灵长类动物模型。
Front Cell Infect Microbiol. 2024 Dec 3;14:1493885. doi: 10.3389/fcimb.2024.1493885. eCollection 2024.
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Regulators of placental antibody transfer through a modeling lens.通过建模视角看胎盘抗体转移的调控。
Nat Immunol. 2024 Nov;25(11):2024-2036. doi: 10.1038/s41590-024-01971-1. Epub 2024 Oct 8.
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FcRn-enhancing mutations lead to increased and prolonged levels of the HIV CCR5-blocking monoclonal antibody leronlimab in the fetuses and newborns of pregnant rhesus macaques.FcRn 增强突变导致怀孕恒河猴胎儿和新生儿体内 HIV CCR5 阻断性单克隆抗体 lerolimumab 的水平升高和持续时间延长。
MAbs. 2024 Jan-Dec;16(1):2406788. doi: 10.1080/19420862.2024.2406788. Epub 2024 Sep 26.
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Hybrid response to SARS-CoV-2 and C after an OMV-adjuvanted immunization in mice and their offspring.在小鼠及其后代中，用 OMV 佐剂免疫后对 SARS-CoV-2 和 C 的混合反应。
Hum Vaccin Immunother. 2024 Dec 31;20(1):2346963. doi: 10.1080/21645515.2024.2346963. Epub 2024 May 15.
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Translational Utility of the Nonhuman Primate Model.非人类灵长类动物模型的转化应用。
Biol Psychiatry Cogn Neurosci Neuroimaging. 2022 May;7(5):491-497. doi: 10.1016/j.bpsc.2022.03.001. Epub 2022 Mar 10.
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Nonhuman Primates in Translational Research.非人类灵长类动物在转化研究中的应用。
Annu Rev Anim Biosci. 2022 Feb 15;10:441-468. doi: 10.1146/annurev-animal-021419-083813.
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Special Issue "Immune Ontogeny and Vaccination in Early Life: How the Non-Human Primate Model Can Help Expand the Current Knowledge in Pediatric Immunology and Infectious Diseases Research".特刊“生命早期的免疫发育与疫苗接种：非人灵长类动物模型如何助力拓展儿科免疫学和传染病研究的现有知识”
Vaccines (Basel). 2021 Sep 12;9(9):1014. doi: 10.3390/vaccines9091014.
本文引用的文献
1
Building the Next Generation of Humanized Hemato-Lymphoid System Mice.构建新一代人源化血液-淋巴系统小鼠。
Front Immunol. 2021 Feb 22;12:643852. doi: 10.3389/fimmu.2021.643852. eCollection 2021.
2
Compromised SARS-CoV-2-specific placental antibody transfer.SARS-CoV-2 特异性胎盘抗体转移受损。
Cell. 2021 Feb 4;184(3):628-642.e10. doi: 10.1016/j.cell.2020.12.027. Epub 2020 Dec 23.
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Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates.评估 mRNA-1273 疫苗对 SARS-CoV-2 在非人类灵长类动物中的效果。
N Engl J Med. 2020 Oct 15;383(16):1544-1555. doi: 10.1056/NEJMoa2024671. Epub 2020 Jul 28.
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FcRn, but not FcγRs, drives maternal-fetal transplacental transport of human IgG antibodies.FcRn 而非 FcγRs 介导人 IgG 抗体经胎盘的母子间转运。
Proc Natl Acad Sci U S A. 2020 Jun 9;117(23):12943-12951. doi: 10.1073/pnas.2004325117. Epub 2020 May 27.
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Reference values of leukocyte and lymphocytes populations in umbilical cord and capillary blood in healthy Mexican newborns.健康墨西哥新生儿脐带血和毛细血管血中白细胞及淋巴细胞群体的参考值
Allergol Immunopathol (Madr). 2020 May-Jun;48(3):295-305. doi: 10.1016/j.aller.2019.12.009. Epub 2020 Apr 17.
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Progressive improvement in the transfer of maternal antibody across the order Primates.灵长目动物中母体抗体转移的逐步改善。
Am J Primatol. 1994;32(1):51-55. doi: 10.1002/ajp.1350320106.
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Adenovectors encoding RSV-F protein induce durable and mucosal immunity in macaques after two intramuscular administrations.编码呼吸道合胞病毒融合蛋白（RSV-F）的腺病毒载体在两次肌肉注射后可在猕猴体内诱导持久的黏膜免疫。
NPJ Vaccines. 2019 Dec 20;4:54. doi: 10.1038/s41541-019-0150-4. eCollection 2019.
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Adjuvants Enhance the Induction of Germinal Center and Antibody Secreting Cells in Spleen and Their Persistence in Bone Marrow of Neonatal Mice.佐剂增强新生小鼠脾脏生发中心和抗体分泌细胞的诱导及其在骨髓中的持续存在。
Front Immunol. 2019 Sep 26;10:2214. doi: 10.3389/fimmu.2019.02214. eCollection 2019.
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Minipigs as a neonatal animal model for tuberculosis vaccine efficacy testing.小型猪作为结核病疫苗效力测试的新生动物模型。
Vet Immunol Immunopathol. 2019 Sep;215:109884. doi: 10.1016/j.vetimm.2019.109884. Epub 2019 Jul 26.
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Maternal Antibodies Inhibit Neonatal and Infant Responses to Vaccination by Shaping the Early-Life B Cell Repertoire within Germinal Centers.母体抗体通过在生发中心内塑造早期 B 细胞库来抑制新生儿和婴儿对疫苗接种的反应。
Cell Rep. 2019 Aug 13;28(7):1773-1784.e5. doi: 10.1016/j.celrep.2019.07.047.
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