Gilstrap L C, Bawdon R E, Burris J
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical School, Dallas.
Obstet Gynecol. 1988 Jul;72(1):124-5.
Levels of five antibiotics used in treating chorioamnionitis were measured in maternal and cord blood and placenta. Ampicillin provided the highest ratio of cord to maternal blood (0.71). Gentamicin was also relatively high in this respect and also had the highest placenta to maternal blood ratio (3.97). Based on these findings, the commonly used combination of ampicillin and gentamicin seems appropriate, although additional anaerobic coverage may be needed.
在母体血液、脐带血和胎盘中测量了用于治疗绒毛膜羊膜炎的五种抗生素的水平。氨苄西林的脐带血与母体血液的比率最高（0.71）。庆大霉素在这方面也相对较高，并且胎盘与母体血液的比率最高（3.97）。基于这些发现，常用的氨苄西林和庆大霉素联合使用似乎是合适的，尽管可能需要额外的抗厌氧菌覆盖。
