Gómez-Salgado Juan, Fagundo-Rivera Javier, Ortega-Moreno Mónica, Allande-Cussó Regina, Ayuso-Murillo Diego, Ruiz-Frutos Carlos
Department of Sociology, Social Work and Public Health, Faculty of Labour Sciences, University of Huelva, 21007 Huelva, Spain.
Safety and Health Postgraduate Programme, Universidad Espíritu Santo, Guayaquil 092301, Ecuador.
Cancers (Basel). 2021 Mar 23;13(6):1470. doi: 10.3390/cancers13061470.
Night work has been highlighted by the International Agency for Research on Cancer (IARC) as a likely carcinogenic factor for humans, associated with breast cancer and professions that require continuity of work. Knowing the impact that short and long-term night work has on the nurses' collective seems a priority, therefore, this study aims to analyse the relationship between night work and the development of breast cancer risk factors in nurses. For this, a cross-sectional study through an online questionnaire on breast cancer risk variables and working life was designed. The study was conducted in Spain and the sample consisted of 966 nurses, of whom 502 were healthy participants and 56 were breast cancer patients. These two groups were compared in the analyses. A descriptive analysis was performed, and the relationship was tested using χ2 independence test and OR calculation. The CHAID (Chi Square Automatic Interaction Detection) data mining method allowed for the creation of a segmentation tree for the main risk variables. The most significant risk variables related to working life have been the number of years worked, nights worked throughout life, and years working more than 3 nights per month. Exceeding 16 years of work has been significant for women and men. When the time worked is less than 16 years, the number of cases increases if there is a family history of cancer and if there have been more than 500 nights of work. High-intensity night work seems more harmful at an early age. The accumulation of years and nights worked increase the risk of breast cancer when factors such as sleep disturbance, physical stress, or family responsibilities come together.
国际癌症研究机构（IARC）已将夜班列为对人类可能的致癌因素，与乳腺癌以及需要持续工作的职业相关。因此，了解短期和长期夜班对护士群体的影响似乎是当务之急，本研究旨在分析夜班与护士患乳腺癌风险因素发展之间的关系。为此，设计了一项通过在线问卷对乳腺癌风险变量和工作生活进行的横断面研究。该研究在西班牙进行，样本包括966名护士，其中502名是健康参与者，56名是乳腺癌患者。在分析中对这两组进行了比较。进行了描述性分析，并使用χ2独立性检验和OR计算来检验这种关系。CHAID（卡方自动交互检测）数据挖掘方法允许为主要风险变量创建一个分割树。与工作生活相关的最显著风险变量是工作年限、一生中的夜班次数以及每月工作超过3个夜班的年限。工作超过16年对女性和男性都具有显著性。当工作时间少于16年时，如果有癌症家族史且工作超过500个夜班，病例数会增加。高强度夜班在年轻时似乎更有害。当睡眠障碍、身体压力或家庭责任等因素同时出现时，工作年限和夜班次数的累积会增加患乳腺癌的风险。
