Lee Hoyoung, Lee Kijeong, Son Serhim, Kim Young-Chan, Kwak Ji Won, Kim Hyeon Geun, Lee Sang Hag, Kim Tae Hoon
Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Korea University, Seoul 02841, Korea.
Department of Biostatistics, Korea University College of Medicine, Seoul 02841, Korea.
Int J Environ Res Public Health. 2021 Mar 12;18(6):2889. doi: 10.3390/ijerph18062889.
An association between fiber intake and allergic diseases in children has been reported; however, many studies have not been conducted to assess this association in adults. We aimed to evaluate the association between dietary fiber intake and allergic diseases (asthma, allergic rhinitis, and atopic dermatitis) among 10,479 adults using data from the Korean National Health and Nutrition Examination Survey (2010-2011). As dietary fiber intake increased, the prevalence of asthma (Q4 adjusted odds ratio (OR): 0.656; 95% confidence interval (CI): 0.48-0.91, for trend < 0.0001) and atopic dermatitis (Q3 crude OR: 0.746; 95% CI: 0.57-0.98; Q4 adjusted OR: 0.712; 95% CI: 0.50-1.01, for trend < 0.0001) decreased. The prevalence of allergic rhinitis (Q2 adjusted OR: 0.840; 95% CI: 0.70-1.00, for trend < 0.0001) tended to decrease, especially in males. Subgroup analysis revealed that fiber intake reduced allergic rhinitis symptoms, including watery rhinorrhea (Q3 adjusted OR: 0.734; 95% CI: 0.55-0.97; Q4 adjusted OR: 0.722; 95% CI: 0.54-0.97) and dog allergen sensitization (Q3 adjusted OR: 0.319; 95% CI: 0.13-0.82; Q4 adjusted OR: 0.338; 95% CI: 0.13-0.86), exclusively in males. Thus, dietary fiber intake influences allergic diseases in adults, especially males.
已有报道称儿童膳食纤维摄入量与过敏性疾病之间存在关联；然而，尚未开展许多研究来评估成年人中的这种关联。我们旨在利用韩国国家健康与营养检查调查（2010 - 2011年）的数据，评估10479名成年人的膳食纤维摄入量与过敏性疾病（哮喘、过敏性鼻炎和特应性皮炎）之间的关联。随着膳食纤维摄入量的增加，哮喘的患病率（第四分位调整优势比（OR）：0.656；95%置信区间（CI）：0.48 - 0.91，趋势P值<0.0001）和特应性皮炎的患病率（第三分位粗OR：0.746；95% CI：0.57 - 0.98；第四分位调整OR：0.712；95% CI：0.50 - 1.01，趋势P值<0.0001）降低。过敏性鼻炎的患病率（第二分位调整OR：0.840；95% CI：0.70 - 1.00，趋势P值<0.0001）有降低趋势，尤其是在男性中。亚组分析显示，膳食纤维摄入减少了过敏性鼻炎症状方面，包括水样鼻溢（第三分位调整OR：0.734；95% CI：0.55 - 0.97；第四分位调整OR：0.722；95% CI：0.54 - 0.97）和对狗过敏原致敏（第三分位调整OR：0.319；95% CI：0.13 - 0.82；第四分位调整OR：0.338；95% CI：0.13 - 0.86），且仅在男性中如此。因此，膳食纤维摄入量会影响成年人的过敏性疾病，尤其是男性。
