Candelaria-Dueñas Sebastián, Serrano-Parrales Rocío, Ávila-Romero Marisol, Meraz-Martínez Samuel, Orozco-Martínez Julieta, Ávila-Acevedo José Guillermo, García-Bores Ana María, Cespedes-Acuña Carlos L, Peñalosa-Castro Ignacio, Hernandez-Delgado Tzasna
Laboratory of Natural Products Bioactivity, UBIPRO, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Av. de los Barrios No. 1, Los Reyes Iztacala, Tlalnepantla 54090, Estado de México, Mexico.
Laboratory of Phytochemistry, UBIPRO, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Av. de los Barrios No. 1, Los Reyes Iztacala, Tlalnepantla 54090, Estado de México, Mexico.
Antibiotics (Basel). 2021 Mar 12;10(3):295. doi: 10.3390/antibiotics10030295.
In Tehuacán-Cuicatlán valley (Mexico), studies have been carried out on the essential oils of medicinal plants with antimicrobial activity and it was found that they present compounds in common such as: α-pinene, β-pinene, carvacrol, eugenol, limonene, myrcene, ocimene, cineole, methyl salicylate, farnesene, and thymol. The goal of this study was to assess the antimicrobial activity of essential oils' compounds. The qualitative evaluation was carried out by the Kirby Baüer agar diffusion technique in Gram-positive bacteria (11 strains), Gram-negative bacteria (18 strains), and yeasts (8 strains). For the determination of the minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), the agar dilution method was used. All the evaluated compounds presented antimicrobial activity. The compounds eugenol and carvacrol showed the largest inhibition zones. Regarding yeasts, the compounds ocimene, cineole, and farnesene did not show any activity. The compounds eugenol, carvacrol, and thymol presented the lowest MIC; bactericidal effect was observed at MIC level for 75MR, 128 MR, and CUSI, for different compounds, eugenol, carvacrol, and thymol. Finally, this study shows that the essential oils of plants used by the population of Tehuacán-Cuicatlán valley share compounds and some of them have antibacterial and fungicidal activity.
在墨西哥的特瓦坎-库伊卡特兰山谷，人们对具有抗菌活性的药用植物精油进行了研究，发现它们含有一些共同的化合物，如：α-蒎烯、β-蒎烯、香芹酚、丁香酚、柠檬烯、月桂烯、罗勒烯、桉叶素、水杨酸甲酯、法呢烯和百里香酚。本研究的目的是评估精油化合物的抗菌活性。通过Kirby Baüer琼脂扩散技术对革兰氏阳性菌（11株）、革兰氏阴性菌（18株）和酵母菌（8株）进行了定性评估。采用琼脂稀释法测定最低抑菌浓度（MIC）和最低杀菌浓度（MBC）。所有评估的化合物均具有抗菌活性。丁香酚和香芹酚的抑菌圈最大。对于酵母菌，罗勒烯、桉叶素和法呢烯没有表现出任何活性。丁香酚、香芹酚和百里香酚的MIC最低；对于不同的化合物丁香酚、香芹酚和百里香酚，在MIC水平对75MR、128MR和CUSI观察到杀菌效果。最后，本研究表明，特瓦坎-库伊卡特兰山谷居民使用的植物精油含有共同的化合物，其中一些具有抗菌和杀真菌活性。
