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自身免疫性疾病及其口腔表现:诊断与临床管理。

Autoimmune Diseases and Their Manifestations on Oral Cavity: Diagnosis and Clinical Management.

机构信息

Department of Oral and Maxillo-Facial Sciences, Sapienza University of Rome, Viale Regina Elena 287a, 00161 Rome, Italy.

出版信息

J Immunol Res. 2018 May 27;2018:6061825. doi: 10.1155/2018/6061825. eCollection 2018.

DOI:10.1155/2018/6061825
PMID:29977929
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5994274/
Abstract

Oral signs are frequently the first manifestation of autoimmune diseases. For this reason, dentists play an important role in the detection of emerging autoimmune pathologies. Indeed, an early diagnosis can play a decisive role in improving the quality of treatment strategies as well as quality of life. This can be obtained thanks to specific knowledge of oral manifestations of autoimmune diseases. This review is aimed at describing oral presentations, diagnosis, and treatment strategies for systemic lupus erythematosus, Sjögren syndrome, pemphigus vulgaris, mucous membrane pemphigoid, and Behcet disease.

摘要

口腔症状通常是自身免疫性疾病的第一表现。因此,牙医在发现新出现的自身免疫性疾病方面发挥着重要作用。事实上,早期诊断可以在改善治疗策略的质量以及生活质量方面发挥决定性作用。这可以通过对自身免疫性疾病的口腔表现的具体了解来实现。本文旨在描述系统性红斑狼疮、干燥综合征、寻常型天疱疮、黏膜类天疱疮和白塞病的口腔表现、诊断和治疗策略。

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Behçet's disease: New insights into pathophysiology, clinical features and treatment options.贝赫切特病:病理生理学、临床特征和治疗选择的新见解。
Autoimmun Rev. 2018 Jun;17(6):567-575. doi: 10.1016/j.autrev.2017.12.006. Epub 2018 Apr 6.
2
Spectrum of orocutaneous disease associations: Immune-mediated conditions.口皮疾病关联的谱:免疫介导的病症。
J Am Acad Dermatol. 2017 Nov;77(5):795-806. doi: 10.1016/j.jaad.2017.02.019.
3
Reviewing primary Sjögren's syndrome: beyond the dryness - From pathophysiology to diagnosis and treatment.原发性干燥综合征综述:超越干燥——从病理生理学到诊断与治疗
Int J Med Sci. 2017 Feb 23;14(3):191-200. doi: 10.7150/ijms.17718. eCollection 2017.
4
Orofacial manifestations in patients with inflammatory rheumatic diseases.炎症性风湿病患者的口腔颌面部表现。
Best Pract Res Clin Rheumatol. 2016 Oct;30(5):826-850. doi: 10.1016/j.berh.2016.09.013. Epub 2016 Nov 18.
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Behçet's disease: A comprehensive review with a focus on epidemiology, etiology and clinical features, and management of mucocutaneous lesions.白塞病:一篇全面综述,重点关注流行病学、病因学、临床特征以及黏膜皮肤病变的管理。
J Dermatol. 2016 Jun;43(6):620-32. doi: 10.1111/1346-8138.13381. Epub 2016 Apr 14.
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Treatment of cutaneous lupus erythematosus: current practice variations.皮肤红斑狼疮的治疗:当前的实践差异
Lupus. 2016 Aug;25(9):964-72. doi: 10.1177/0961203316628997. Epub 2016 Jan 27.
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Br J Dermatol. 2016 Jul;175(1):113-21. doi: 10.1111/bjd.14410. Epub 2016 Apr 27.
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J Am Acad Dermatol. 2016 Apr;74(4):746-53. doi: 10.1016/j.jaad.2015.11.008. Epub 2016 Jan 11.
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Br J Dermatol. 2016 May;174(5):1022-9. doi: 10.1111/bjd.14351. Epub 2016 Mar 7.
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Int J Paediatr Dent. 2016 Sep;26(5):351-6. doi: 10.1111/ipd.12207. Epub 2015 Oct 6.