Graham D F
Br Med J. 1977 Nov 26;2(6099):1375-7. doi: 10.1136/bmj.2.6099.1375.
The clinical details of 100 patients with proved acute appendicitis were compared with those of 100 patients with perforating or gangrenous appendicitis. Twenty features were found to be significantly different between the two groups. This information was incorporated into a computer data base and used in the differential diagnosis of abdominal pain. A program written to predict the probability that gangrene or perforation was present in patients with appendicitis gave a diagnostic accuracy over 91%. A clinical scoring index, which accurately predicted the state of the appendix in 88% of patients, was constructed from the significant differences between the two groups. When clinical scoring or computer analysis predicts a high probability of perforation or gangrene in patients with appendicitis, surgery should be performed without delay.
将100例确诊为急性阑尾炎患者的临床细节与100例穿孔性或坏疽性阑尾炎患者的临床细节进行了比较。发现两组之间有20个特征存在显著差异。这些信息被纳入计算机数据库，并用于腹痛的鉴别诊断。一个用于预测阑尾炎患者出现坏疽或穿孔可能性的程序，其诊断准确率超过91%。根据两组之间的显著差异构建了一个临床评分指数，该指数能准确预测88%患者的阑尾状况。当临床评分或计算机分析预测阑尾炎患者穿孔或坏疽的可能性很高时，应立即进行手术。
