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1970年至1982年一家地区综合医院胃和十二指肠溃疡手术治疗的经验

A district general hospital experience of surgical treatment of gastric and duodenal ulcer from 1970 to 1982.

作者信息

McEntee G, Ryan W, Peel A L, Rosenberg I L, Devlin H B

机构信息

Department of Surgery, North Tees General Hospital, Stockton-on-Tees, England.

出版信息

Surg Gynecol Obstet. 1988 Jul;167(1):53-60.

PMID:3381186
Abstract

Seven hundred and thirteen patients who had undergone 793 operations for peptic ulcer disease during the years 1970 to 1982 were subsequently referred to a gastric follow-up clinic. The indications for initial elective surgical treatment (514) were failed medical management (448), recent hemorrhage (32) and obstruction of gastric outflow (34); for initial emergency surgical treatment (199), the indications were hemorrhage (97) and perforation (102). Reoperation was required in 80 patients-previous perforation (40), recurrent ulcer (32), reperforation (three), hemorrhage (three) and obstruction of gastric outflow (two). The over-all postoperative mortality rate was 4.2 per cent (33 of 713); 15 deaths occurred after elective surgical treatment (2.5 per cent) and 18 after emergency surgical treatment (8.6 per cent). The postoperative morbidity expressed in terms of duration of postoperative stay was unaltered for each procedure throughout the study period. Follow-up attendance rates at one, three, five and ten years were 86, 85, 74 and 28 per cent, respectively. Iron deficiency anemia was detected in 13.6 per cent of gastric resection procedures and 1.6 per cent of vagotomy and drainage procedures. No instances of macrocytic anemia and only two instances of asymptomatic metabolic bone disease were recorded. By providing accurate data for surgical audit, which suggested that screening for metabolic sequelae in the first decade after surgical treatment is not indicated and which resulted in alteration of policy toward peptic ulcer perforation, a specific follow-up clinic has proved valuable in formulating the over-all management policy regarding surgical treatment for peptic ulcer.

摘要

1970年至1982年间,713例接受了793次消化性溃疡疾病手术的患者随后被转诊至一家胃部随访诊所。初次择期手术治疗(514例)的指征为内科治疗失败(448例)、近期出血(32例)和胃流出道梗阻(34例);初次急诊手术治疗(199例)的指征为出血(97例)和穿孔(102例)。80例患者需要再次手术——既往穿孔(40例)、复发性溃疡(32例)、再次穿孔(3例)、出血(3例)和胃流出道梗阻(2例)。总体术后死亡率为4.2%(713例中的33例);择期手术治疗后有15例死亡(2.5%),急诊手术治疗后有18例死亡(8.6%)。在整个研究期间,以术后住院时间表示的术后发病率在每种手术中均未改变。1年、3年、5年和10年的随访就诊率分别为86%、85%、74%和28%。在胃切除术病例中,13.6%检测到缺铁性贫血,在迷走神经切断术和引流术病例中,1.6%检测到缺铁性贫血。未记录到大细胞性贫血病例,仅记录到2例无症状代谢性骨病病例。通过为手术审计提供准确数据,表明术后第一个十年无需筛查代谢后遗症,且该数据导致了对消化性溃疡穿孔治疗策略的改变,一家专门的随访诊所已证明在制定消化性溃疡手术治疗的总体管理策略方面具有价值。

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