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斯洛伐克产前和产后超声筛查肾脏先天性发育异常的有效性和敏感性。

EFFICACY AND SENSITIVITY OF PRENATAL AND POSTNATAL ULTRASOUND SCREENING OF CONGENITAL DEVELOPMENTAL ANOMALIES OF KIDNEYS IN SLOVAKIA.

机构信息

SLOVAK MEDICAL UNIVERSITY, BRATISLAVA, SLOVAKIA; A. GETLIK CLINIC FOR CHILDREN AND ADOLESCENTS, SLOVAK MEDICAL UNIVERSITY AND UNIVERSITY HOSPITAL OF MEDICINE, BRATISLAVA, SLOVAKIA.

出版信息

Wiad Lek. 2021;74(3 cz 1):450-454.

Abstract

OBJECTIVE

The aim: To compare the effectiveness and sensitivity of prenatal and postnatal diagnostics in the diagnosis of congenital malformations of the urinary system in the Slovak Republic.

PATIENTS AND METHODS

Materials and methods: Data of postnatal sonographic screening of congenital developmental malformations of the urinary system in Slovak Republic including 2017 were identified and updated using a questionnaire survey, 38,496 newborns were involved. Statistical data on the proportion of prenatal diagnosis for the years 1995, 2000, 2005, 2008 and 2013-2016 were provided from the National Register of Congenital Defects. The chi2-test and t-test were applied to assess the sensitivity differences.

RESULTS

Results: The study showed a low sensitivity of prenatal diagnosis with its maximum in 2016, reaching 32.3% and a minimum in 2005-2008 (8.0 - 8.4%). The sensitivity of postnatal diagnostics for selected years has always been a stable indicator and reaches 99.6%.

CONCLUSION

Conclusions: Available statistical data confirm that prenatal diagnostics of congenital developmental malformations of the urinary system in the Slovak Republic is not perfect. Our work underlines the importance, or we should rather say inevitability of postnatal ultrasound screening for congenital developmental anomalies in the kidneys.

摘要

目的

比较产前和产后诊断在斯洛伐克共和国诊断泌尿系统先天性畸形的有效性和敏感性。

患者和方法

材料和方法:使用问卷调查确定并更新了斯洛伐克共和国包括 2017 年在内的产后超声筛查先天性发育性泌尿系统畸形的数据,涉及 38496 名新生儿。从国家先天性缺陷登记处提供了 1995 年、2000 年、2005 年、2008 年和 2013-2016 年产前诊断比例的统计数据。应用卡方检验和 t 检验评估敏感性差异。

结果

研究显示产前诊断的敏感性较低,其最大值出现在 2016 年,达到 32.3%,最小值出现在 2005-2008 年(8.0-8.4%)。选定年份的产后诊断敏感性一直是一个稳定的指标,达到 99.6%。

结论

现有统计数据证实,斯洛伐克共和国泌尿系统先天性发育畸形的产前诊断并不完善。我们的工作强调了产后超声筛查肾脏先天性发育异常的重要性,或者我们应该说是必然性。

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