Joensen F
Paediatrisk afdeling, Arhus Kommunehospital.
Ugeskr Laeger. 1996 Apr 15;158(16):2246-50.
The aim of this study was to determine the incidence of diagnosed congenital malformations of the kidneys, urinary and gastrointestinal tracts at two years of age in an unselected population of 8952 children born in three Danish counties in 1991. Further, to review how frequently these conditions were detected by obstetric ultrasound examination since no systematic screening for malformations was performed in 1991 in this area. Twenty-three children were found with congenital malformations of the kidneys or urinary tract which gives an incidence of 0.26%. Although 16 of the mothers had been examined with ultrasound during pregnancy, the malformation was only diagnosed or suspected in three of the 23 children. Fourteen children had gastrointestinal malformations, eight were scanned prenatally and only one (diaphragmatic hernia) was diagnosed prenatally. Thus malformations in kidneys, urinary tract or gastrointestinal tract were rarely diagnosed prenatally by ultrasound although 70% of the mothers were scanned at least once during pregnancy.
本研究的目的是确定1991年出生在丹麦三个县的8952名未经过挑选的儿童在两岁时被诊断出的肾脏、泌尿和胃肠道先天性畸形的发病率。此外,鉴于1991年该地区未进行系统的畸形筛查,本研究还要评估通过产科超声检查发现这些病症的频率。发现有23名儿童患有肾脏或泌尿系统先天性畸形,发病率为0.26%。尽管其中16名母亲在孕期接受了超声检查,但在这23名儿童中,只有3名被诊断或怀疑患有畸形。14名儿童患有胃肠道畸形,其中8名在产前接受了扫描,只有1名(膈疝)在产前被诊断出来。因此,尽管70%的母亲在孕期至少接受了一次超声检查,但肾脏、泌尿系统或胃肠道畸形很少能通过超声在产前被诊断出来。