Department of Ophthalmology (J.Y., Y.Z.), Shanghai Qingpu Traditional Chinese Medicine Hospital, Shanghai, China; and Department of Ophthalmology (X.-Q.L., D.-H.W.), LongHua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Eye Contact Lens. 2021 Jun 1;47(6):341-346. doi: 10.1097/ICL.0000000000000782.
To investigate the lower lid margin thickness (LLMT) from the posterior lash line to the anterior edge of tear meniscus with Oculus Keratograph 4 (K4).
This was a prospective, single-center, observational study. A total of 90 volunteers aged 18 to 79 years with no ocular diseases were included in this study. The LLMT of 90 subjects was measured twice by the same person with K4. To determine the reliability of K4, measuring the LLMT of 30 normal subjects was separately performed by two operators.
The LLMT measurements with K4 between two operators demonstrated a good reproducibility (0.94±0.18 vs. 0.96±0.16 mm; intraclass correlation coefficient=0.88; P=0.18). The mean age of 90 volunteers (42 men and 48 women) was 45.5±14.1 years. The LLMT was 0.95±0.17 mm, which was a significant positive correlation with age (rs=0.57; P<0.001). In addition, there was no significant difference in the LLMT between genders (0.97±0.16 vs. 0.93±0.18 mm; P=0.32).
We found that K4 was a reliable tool in the LLMT measurements, and the LLMT seemed to be closely related to age but not to gender.
使用 Oculus Keratograph 4(K4)研究从后睫毛线到泪膜前缘的下眼睑缘厚度(LLMT)。
这是一项前瞻性、单中心、观察性研究。本研究共纳入 90 名年龄在 18 至 79 岁之间、无眼部疾病的志愿者。用 K4 两次测量 90 名受试者的 LLMT。为了确定 K4 的可靠性,由两名操作人员分别对 30 名正常受试者的 LLMT 进行了单独测量。
两名操作人员用 K4 测量的 LLMT 具有良好的可重复性(0.94±0.18 与 0.96±0.16mm;组内相关系数=0.88;P=0.18)。90 名志愿者(42 名男性和 48 名女性)的平均年龄为 45.5±14.1 岁。LLMT 为 0.95±0.17mm,与年龄呈显著正相关(rs=0.57;P<0.001)。此外,性别之间的 LLMT 无显著差异(0.97±0.16 与 0.93±0.18mm;P=0.32)。
我们发现 K4 是一种可靠的 LLMT 测量工具,LLMT 似乎与年龄密切相关,但与性别无关。