脆性 X 智力低下 1 号前突变及广泛自闭症表型中的母体语用困难：与个体和家庭结局的关联。
Maternal Pragmatic Language Difficulties in the FMR1 Premutation and the Broad Autism Phenotype: Associations with Individual and Family Outcomes.
机构信息
Department of Communication Sciences and Disorders, University of South Carolina, 1705 College Street, Columbia, SC, 29208, USA.
Department of Psychiatry and Behavioral Sciences and MIND Institute, University of California Davis Health, 2825 50th Street, Room 2335, Sacramento, CA, 95817, USA.
出版信息
J Autism Dev Disord. 2022 Feb;52(2):835-851. doi: 10.1007/s10803-021-04980-3. Epub 2021 Apr 4.
Abstract
Broader phenotypes associated with genetic liability, including mild difficulties with pragmatic language skills, have been documented in mothers of children with autism spectrum disorder (ASD) and mothers of children with fragile X syndrome (FXS). This study investigated the relationship between pragmatic difficulties and indicators of maternal well-being and family functioning. Pragmatic difficulty was associated with loneliness in mothers of children with ASD or FXS, and with depression, decreased life satisfaction, and poorer family relationship quality in mothers of children with FXS only. Results inform subtle maternal pragmatic language difficulties as a risk factor that that may contribute to reduced health and well-being, informing tailored support services to better meet the unique needs of families of children with ASD or FXS.
摘要
在自闭症谱系障碍（ASD）儿童的母亲和脆性 X 综合征（FXS）儿童的母亲中，已经记录到与遗传易感性相关的更广泛表型，包括轻微的语用语言技能困难。本研究调查了语用困难与母亲幸福感和家庭功能的指标之间的关系。语用困难与 ASD 或 FXS 儿童的母亲的孤独感有关，与 FXS 儿童的母亲的抑郁、生活满意度降低和较差的家庭关系质量有关。研究结果表明，母亲语用语言方面的细微困难是一个风险因素，可能会导致健康和幸福感下降，为更好地满足 ASD 或 FXS 儿童家庭的独特需求提供有针对性的支持服务。
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