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女性中的双叶状颗粒性子宫内膜细胞:我们具有挑战性但值得的经验。

Bilobed PMMC in Females: Our Challenging yet Meritorious Experience.

作者信息

Jayaprakash Dipin, Nandy Kunal, Tripathi Umank, Mithi Mohamad Taher, Vyas Ronak, Sadangi Sudam

机构信息

Department of Surgical Oncology, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat India.

出版信息

Indian J Surg Oncol. 2021 Mar;12(1):39-47. doi: 10.1007/s13193-020-01223-2. Epub 2020 Oct 8.

Abstract

The gold standard reconstructive options for full-thickness defect of the oral cavity after resection of malignant lesions are the free flaps. But in developing nations due to resource constraints, it cannot be offered to all. Hence, pectoralis major myocutaneous (PMMC) flap as bilobed flaps is most commonly used. Bilobed flaps are technically demanding, and in females, it is more challenging due to higher complication rates especially in large breasts. There has been no major reported data evaluating outcomes of bilobed PMMC in females. This is a retrospective evaluation of outcomes of patients who underwent the bilobed PMMC flap reconstruction for full-thickness defect of the oral cavity after resection of malignant lesions from June 2018 to December 2019. Out of 80 patients, all patients ultimately had adequate tissue coverage for the defect with acceptable facial aesthetics. Functional outcomes with regards to oral continence, speech and swallowing were encouraging. Our study had 33.75% flap-related complications. Fifteen percent of patients developed varying degrees of flap loss, of which only 3.75% had total flap loss and 11.25% had partial flap loss which was managed accordingly. Our study concludes that with careful planning, raising of flap based on sound anatomic concepts and applying oncoplastic techniques, shortcomings of bilobed female PMMC can be addressed and still used as suitable alternatives for free flap for full-thickness oral cavity defects in limited resource settings.

摘要

恶性病变切除术后口腔全层缺损的金标准重建方法是游离皮瓣。但在发展中国家,由于资源限制,无法为所有患者提供游离皮瓣。因此,胸大肌肌皮瓣(PMMC)作为双叶皮瓣是最常用的。双叶皮瓣技术要求高,对于女性患者来说,由于并发症发生率较高,尤其是在乳房较大的情况下,手术更具挑战性。目前尚无关于女性双叶PMMC皮瓣手术效果评估的主要报道数据。这是一项回顾性研究,评估了2018年6月至2019年12月期间因恶性病变切除术后口腔全层缺损而接受双叶PMMC皮瓣重建的患者的手术效果。在80例患者中,所有患者最终均获得了足够的组织覆盖缺损,面部美观度可接受。在口腔节制、言语和吞咽方面的功能结果令人鼓舞。我们的研究中有33.75%的皮瓣相关并发症。15%的患者出现了不同程度的皮瓣丢失,其中只有3.75%的患者皮瓣完全丢失,11.25%的患者皮瓣部分丢失,并据此进行了相应处理。我们的研究得出结论,通过精心规划,基于合理的解剖概念掀起皮瓣并应用肿瘤整形技术,可以解决女性双叶PMMC皮瓣的缺点,并且在资源有限的情况下,仍然可以作为游离皮瓣用于口腔全层缺损的合适替代方案。

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Bipaddle Pectoralis Major Myocutaneous Flap for Single Stage Reconstruction of Oromandibular Defects.双叶胸大肌肌皮瓣一期修复口腔颌面部缺损
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本文引用的文献

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Bipaddle Pectoralis Major Myocutaneous Flap for Single Stage Reconstruction of Oromandibular Defects.双叶胸大肌肌皮瓣一期修复口腔颌面部缺损
Indian J Otolaryngol Head Neck Surg. 2020 Mar;72(1):44-48. doi: 10.1007/s12070-019-01731-w. Epub 2019 Aug 19.
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PMMC Flap Revisited and its Clinical Outcome in 150 Patients.股薄肌肌皮瓣回顾及其150例患者的临床结果
J Maxillofac Oral Surg. 2020 Mar;19(1):26-31. doi: 10.1007/s12663-019-01228-7. Epub 2019 Apr 23.
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Three-dimensional anatomical vascular distribution in the pectoralis major myocutaneous flap.胸大肌肌皮瓣的三维解剖血管分布
Plast Reconstr Surg. 2005 Apr 15;115(5):1342-52; discussion 1353-4. doi: 10.1097/01.prs.0000156972.66044.5c.
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Para-sternal approach for pectoralis major myocutaneous flap in females.
J Surg Oncol. 2004 Mar 15;85(4):199-201. doi: 10.1002/jso.20034.

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