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Editorial: Understanding the Cytokine Release Syndrome: Toward Improving Cancer Immunotherapy.

作者信息

Martín-Antonio Beatriz

机构信息

Department of Experimental Hematology, Instituto de Investigación Sanitaria-Fundación Jiménez Diaz, Madrid, Spain.

出版信息

Front Immunol. 2021 Mar 19;12:666703. doi: 10.3389/fimmu.2021.666703. eCollection 2021.

DOI:10.3389/fimmu.2021.666703
PMID:33815428
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8017175/
Abstract
摘要

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Nat Med. 2020 Dec;26(12):1878-1887. doi: 10.1038/s41591-020-1061-7. Epub 2020 Oct 5.
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Chimeric antigen receptor-T cells with cytokine neutralizing capacity.嵌合抗原受体-T 细胞具有细胞因子中和能力。
Blood Adv. 2020 Apr 14;4(7):1419-1431. doi: 10.1182/bloodadvances.2019001287.
3
Gasdermin E-mediated target cell pyroptosis by CAR T cells triggers cytokine release syndrome.嵌合抗原受体 T 细胞通过 GSDME 介导热激细胞焦亡引发细胞因子释放综合征。
Sci Immunol. 2020 Jan 17;5(43). doi: 10.1126/sciimmunol.aax7969.
4
IL-6 and ovarian cancer: inflammatory cytokines in promotion of metastasis.白细胞介素-6与卵巢癌：促进转移的炎性细胞因子
Cancer Manag Res. 2018 Dec 5;10:6685-6693. doi: 10.2147/CMAR.S179189. eCollection 2018.
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The significant role of interleukin-6 and its signaling pathway in the immunopathogenesis and treatment of breast cancer.白细胞介素-6 及其信号通路在乳腺癌的免疫发病机制和治疗中的重要作用。
Biomed Pharmacother. 2018 Dec;108:1415-1424. doi: 10.1016/j.biopha.2018.09.177. Epub 2018 Oct 6.
6
Cytokine release syndrome.细胞因子释放综合征。
J Immunother Cancer. 2018 Jun 15;6(1):56. doi: 10.1186/s40425-018-0343-9.
7
Clinical and Biological Correlates of Neurotoxicity Associated with CAR T-cell Therapy in Patients with B-cell Acute Lymphoblastic Leukemia.与 B 细胞急性淋巴细胞白血病患者的 CAR T 细胞治疗相关的神经毒性的临床和生物学相关性。
Cancer Discov. 2018 Aug;8(8):958-971. doi: 10.1158/2159-8290.CD-17-1319. Epub 2018 Jun 7.
8
Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma.阿基仑赛注射液嵌合抗原受体T细胞疗法治疗难治性大B细胞淋巴瘤
N Engl J Med. 2017 Dec 28;377(26):2531-2544. doi: 10.1056/NEJMoa1707447. Epub 2017 Dec 10.
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Balancing the immune response in the brain: IL-10 and its regulation.平衡大脑中的免疫反应：白细胞介素-10及其调节
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